Ultra-Pure Thiomersal

 Batch-Consistent, COA-Backed Quality

our product is a high-purity, analytically validated organomercury compound widely used as an antimicrobial preservative in pharmaceutical, vaccine, and biomedical applications. Manufactured under stringent quality systems, our products delivers exceptional batch-to-batch consistency, regulatory-ready documentation, and global supply reliability.

At SRIRAMCHEM Laboratories Pvt. Ltd., we supply COA-backed products with complete analytical support, ensuring compliance with international quality and safety standards.

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Product Identity & Nomenclature

• IUPAC Name: Ethyl(2-mercaptobenzoato-(2-)-O,S) mercurate(1-) sodium

• Common Names:

  • Sodium ethylmercurithiosalicylate

  • Merthiolate

  • Mercury((o-carboxyphenyl)thio)ethyl sodium salt

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Regulatory & Database Identifiers

• CAS Number: 54-64-8

• EC Number: 200-210-4

• UNII: 2225PI3MOV

• ChEBI: CHEBI:9546

• ChEMBL: ChEMBL508338

• DrugBank: DB11590

• PubChem SID: 461483237

• RTECS: OV8400000

• ECHA InfoCard: 100.000.192

• CompTox (EPA): DTXSID3025540

These identifiers support regulatory filings, pharmacological evaluation, and compliance documentation.

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Chemical & Physical Properties

• Chemical Formula: C₉H₉HgNaO₂S

• Molar Mass: 404.81 g/mol

• Appearance: White to slightly yellow crystalline powder

• Density: 2.508 g/cm³

• Melting Point: 232–233 °C (decomposes)

• Solubility: Highly soluble in water (≈1000 g/L at 20 °C)

• Flash Point: 250 °C

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Chemical Structure & Functional Characteristics

Thiomersal is a thiol (sulfhydryl) compound composed of ethylmercury and thiosalicylate. Its antimicrobial efficacy arises from the controlled release of ethylmercury ions, which inhibit microbial enzymes and cellular metabolism. This mechanism provides broad-spectrum protection against bacteria and fungi, making product highly effective as a preservative in multi-dose formulations.

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Pharmacological Classification

• ATC Code (WHO): D08AK06

• Therapeutic Role: Antimicrobial preservative and topical antiseptic

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Key Applications 

1. Vaccine Preservative

Thiomersal is used in selected vaccine formulations to prevent microbial contamination during manufacturing, storage, and multi-dose usage. This ensures product sterility, safety, and shelf-life stability.

2. Pharmaceutical & Biological Preparations

Used as an antimicrobial agent in injectables, ophthalmic solutions, and biological products, where microbial control is critical.

3. Topical Antiseptic Formulations

Incorporated into ointments, creams, and wound-care products to prevent bacterial growth in minor cuts and skin infections.

4. Contact Lens & Ophthalmic Solutions

Applied in ophthalmic preparations to inhibit microbial contamination and maintain ocular safety.

5. Research & Analytical Applications

Widely used as a reference compound in pharmaceutical R&D, toxicology studies, and method validation.

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Safety, Handling & Hazard Information

• GHS Signal Word: Danger

• Hazard Statements: H300, H310, H330, H373, H410

• Precautionary Statements: P260, P273, P280, P301, P302, P304, P310, P330, P340, P352

• NFPA 704 Rating:

  • Health: 3

  • Flammability: 1

  • Reactivity: 1

⚠️ Professional handling only. Use appropriate PPE and follow regulatory safety guidelines.

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Why Choose SRIRAMCHEM?

• Ultra-High Purity: Manufactured under validated processes

• Batch-Consistent Quality: Reliable reproducibility across lots

• Complete Documentation: COA, MSDS, and analytical data available

• Regulatory-Ready Supply: Suitable for pharma and vaccine use

• Global Distribution Capability: Trusted worldwide

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Packaging, Supply & Customization

• Available in research, pilot, and commercial pack sizes

• Custom specifications and documentation support on request

• Long-term supply agreements available

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Request a Quote or Technical Datasheet

Enhance your pharmaceutical, vaccine, or research formulations with Ultra-Pure Thiomersal from SRIRAMCHEM Laboratories Pvt. Ltd.

📩 Contact us today for pricing, samples, or technical support.