H-Tyr-OtBu

Streamline your peptide synthesis and organic chemistry workflows with H-Tyr-OtBu (CAS No.: 16874-12-7, CAT No.: SRCT-004). Also known as L-tyrosine tert-butyl ester or tert-butyl (S)-2-amino-3-(4-hydroxyphenyl)propanoate, this protected tyrosine derivative is widely used as an amino acid building block in solid-phase peptide synthesis (SPPS), bioconjugation, and the preparation of peptide-based therapeutics. The bulky tert-butyl ester group offers robust protection for the carboxyl function, ensuring selective deprotection and facilitating multi-step peptide assembly.

The molecular formula is C₁₃H₁₉NO₃ and the molecular weight is 237.3 g/mol. H-Tyr-OtBu typically appears as a white crystalline powder, is soluble in methanol and DMSO (up to 100 mg/mL), and should be stored at 2–8 °C in a sealed, dry container, protected from light and moisture. The optical rotation is [α]_D²⁰ = +25° (c=2, ethanol).

Product Highlights

Technical Features & Benefits

• tert-Butyl Ester Protection: Ensures selective and mild deprotection compatible with standard SPPS protocols.
• High Purity: Suitable for pharmaceutical, bioconjugation, and research applications (≥98% by HPLC).
• Stable and Versatile: Stable under inert and dry conditions for long-term storage and reliable use.
• Robust Amino Acid Building Block: Widely applicable for introducing tyrosine residues into peptides, peptidomimetics, and conjugates.
• Batch-Specific Documentation: Supplied with COA and analytical data for each lot.

Application Areas

• Solid-phase peptide synthesis (SPPS) for custom and therapeutic peptides
• Synthesis of modified and labeled peptides for bioconjugation
• Pharmaceutical and medicinal chemistry research
• Preparation of peptide-based drugs, diagnostics, and biomaterials
• Custom synthesis and combinatorial chemistry

Safety & Handling

• Wear gloves, lab coat, and protective eyewear when handling
• Avoid inhalation, ingestion, and direct contact with eyes or skin
• Store tightly sealed, dry, and protected from light at 2–8 °C
• Dispose of in accordance with local regulatory requirements

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Trusted supplier of high-purity protected amino acids since 2013
• Comprehensive batch-specific documentation and COA
• Custom synthesis and scalable supply options
• Expert technical support and prompt customer service

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Enhance your peptide synthesis with SRIRAMCHEM’s H-Tyr-OtBu. Contact us now for pricing, fast delivery, or technical support.