2-Acetylpyridine

Enhance your heterocyclic and coordination chemistry projects with 2-acetylpyridine (CAS No.: 1122-62-9, CAT No.: SRCA-034). This methyl 2-pyridyl ketone derivative serves as a versatile building block and ligand precursor in organic synthesis, metal-ligand complex formation, and pharmaceutical lead optimization.

ith a molecular formula of C₇H₇NO and a molecular weight of 121.14 g/mol, 2-acetylpyridine is typically supplied as a colorless to pale yellow clear liquid with a density of about 1.08 g/mL and a boiling point around 188?189 ?C. It is soluble in water and common organic solvents, and its combination of a pyridine nitrogen and an acetyl carbonyl enables chelation to metal centers and straightforward derivatization into oximes, hydrazones, and thiosemicarbazones for medicinal chemistry applications.

Product Highlights

Technical Features & Benefits

• • Bifunctional Heteroaromatic Ketone: Contains both a pyridine nitrogen and an acetyl carbonyl group, enabling rich reactivity in condensation, nucleophilic addition, and metal-complex formation chemistry.

• • Versatile Ligand Precursor: Forms Schiff bases and related derivatives that act as chelating ligands for transition-metal complexes used in catalysis and materials research.

• • High Purity for R&D: Supplied at 99% purity, suitable for synthetic route scouting, analytical reference work, and lead molecule derivatization.

• • liquid, Easy Handling: Low-melting liquid with moderate boiling point and good solubility profile for straightforward dosing, reaction setup, and scale-up.
  • Flavor and Aroma Applications: Used industrially as a specialty flavor and fragrance ingredient, supporting cross-over projects in fine chemicals and sensory science.

Application Areas

• • Precursor for Schiff bases, oximes, hydrazones, and thiosemicarbazones explored as potential antimalarial and bioactive agents.

• • igand or ligand precursor for transition-metal complexes in homogeneous catalysis, coordination chemistry, and functional materials.

• • Intermediate in the synthesis of heterocyclic fine chemicals, pharmaceuticals, and agrochemical candidates.

• • Component in flavor and fragrance formulations where pyridyl-ketone notes are desired.

• • Research tool in studies of structure-odor relationships, chelation, and heteroaromatic reactivity.

Safety & Handling

• • Wear appropriate PPE, including gloves, safety goggles, and lab coat; avoid skin and eye contact.

• • Handle away from ignition sources; 2-acetylpyridine is a combustible liquid and should be used in a fume hood with adequate ventilation.

• • Store in tightly closed containers in a cool, well-ventilated area, protected from light and air; keep away from strong oxidizing agents.

• • Dispose of contents and containers according to local and national hazardous waste regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• • Strong expertise in heterocyclic building blocks, ligands, and pharmaceutical intermediates with strict quality systems for reproducible performance.

• • ustom synthesis options from milligram to multi-kilogram scale for specialized 2-acetylpyridine derivatives and metal complexes.

• • Comprehensive analytical documentation, including COA and available NMR, GC/HPLC, and LC-MS data to support regulatory and R&D needs.
• Responsive technical team to assist with route design, impurity profiling, and specification development around your project requirements.

Request a Quote or Sample Today! Accelerate your coordination, medicinal, and fine chemicals research with SRIRAMCHEM’s premium 2-acetylpyridine. Contact the expert team for pricing, availability, or to discuss custom synthesis and analytical support.