3-Acetylpyridine

Boost your heterocyclic synthesis and fine chemical projects with 3-acetylpyridine (CAS No.: 350-03-8, CAT No.: SRCA-035). This 1-(pyridin-3-yl)ethanone derivative is an important intermediate for pharmaceuticals, agrochemicals, vitamins (notably niacin/niacinamide), and specialty heterocycles used in medicinal and materials chemistry.

With a molecular formula of C₇H₇NO and a molecular weight of 121.14 g/mol, 3-acetylpyridine is a clear, colorless to yellow-green liquid with a melting point around 11-13°C, boiling point near 220 ?C, density about 1.10?1.11 g/mL, and a characteristic nutty, popcorn-like odor. It dissolves in hot water and organic solvents, and its combination of a pyridine ring and acetyl group makes it a versatile platform for condensation, reduction, and ligand-formation reactions.

Product Highlights

Technical Features & Benefits

• • Key Pyridine Intermediate: Widely used as a raw material in the synthesis of therapeutic drugs, agrochemicals, and niacin-related vitamins.

• • Bifunctional Aromatic Ketone: The 3-acetyl substituent on the pyridine ring supports versatile transformations such as reduction, condensation, and oxime or hydrazone formation in medicinal chemistry workflows.

• • High-Purity Liquid: Supplied typically at 98% purity with defined physical constants, suitable for reproducible R&D, scale-up, and analytical applications.

• • Odor-Active Building Block: Recognized FEMA-listed flavor ingredient with nutty, popcorn-like notes, enabling use in flavor and fragrance research.

• • Proven Industrial Relevance: Employed in commercial processes as an intermediate in routes to risedronate sodium and other value-added fine chemicals.

Application Areas

• • Intermediate in synthesis of pharmaceuticals, including bone resorption inhibitors like risedronate sodium and other nitrogen-containing heterocycles.

• • Building block for niacin/niacinamide-related vitamins and nutraceuticals.

• • Starting material for oximes, hydrazones, and other derivatives used as ligands, probes, or bioactive candidates.

• • Flavor and fragrance ingredient imparting nutty, roasted, and popcorn-like notes at low ppm levels.

• • Research tool in neurotoxin and CNS studies where 3-acetylpyridine is used to model cerebellar dysfunction in vivo.

Safety & Handling

• • Wear suitable PPE including gloves, safety goggles, and lab coat; avoid inhalation, ingestion, and contact with skin or eyes.

• • Toxic if swallowed and irritating to skin and eyes; handle in a fume hood with adequate ventilation and follow institutional safety procedures.

• • Store in tightly closed containers in a cool, well-ventilated, dark place under inert gas; keep away from heat, sparks, open flames, and strong oxidizers.

• • Dispose of residues and contaminated materials as hazardous chemical waste according to local and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• • Deep expertise in pyridine derivatives, pharmaceutical intermediates, and fine chemicals backed by robust quality systems and technical know-how.

• • Custom synthesis and scale-up services for 3-acetylpyridine analogues and downstream intermediates from milligram to multi-kilogram quantities.

• • Comprehensive analytical documentation including COA and available NMR, GC/HPLC, and LC?MS data to support regulatory filings and advanced R&D.

• Agile, responsive customer support to align supply, impurity control, and specifications with your project timelines and technical requirements.

Request a Quote or Sample Today! Drive your pharmaceutical, vitamin, and fine chemical development programs forward with SRIRAMCHEM?s premium 3-acetylpyridine. Contact the expert team for pricing, availability, or to discuss custom synthesis and analytical support needs.