Z-Trp-OMe

Z-Trp-OMe (CAS No.: 2717-76-2, CAT No.: SRCZ-027) is a high-purity N-protected tryptophan methyl ester, widely used as a building block in advanced peptide synthesis and medicinal chemistry. Known also as benzyloxycarbonyltryptophan methyl ester or Cbz-tryptophan methyl ester, this compound features a classic benzyloxycarbonyl (Cbz or Z) protecting group on the α-amino group and a methyl esterified carboxyl terminus. This configuration provides exceptional selectivity during peptide chain assembly and allows for streamlined deprotection and sequential coupling.

Delivered as a white to off-white crystalline powder with outstanding purity (≥98%), Z-Trp-OMe demonstrates strong chemical stability and dissolves well in standard peptide synthesis solvents including DMSO, DMF, and methanol. Its molecular formula is C₁₈H₁₈N₂O₄ with a molecular weight of 326.35 g/mol, making it suitable for both manual and automated solid-phase or solution-phase peptide synthesis workflows, as well as efficient research-scale and process development applications.

Product Highlights

Technical Features & Benefits

• Cbz N-Protection and Methyl Ester: Facilitates highly selective stepwise peptide synthesis and controlled deprotection workflows.
• High Purity & Stability: Stringent QC supports robust repeatability and reliability across automated and batch processes.
• Excellent Solubility: Integrates with standard peptide solvents for flexible methodology and workflow optimization.
• Versatile Intermediate: Indispensable for constructing tryptophan-containing peptides, custom biomolecules, and peptidomimetic structures.
• Batch-to-Batch Consistency: Guarantees reproducible results for scale-up and analytical development.

Application Areas

• Protected tryptophan methyl ester for solid-phase and solution-phase peptide synthesis
• Tool for advanced peptidomimetic research and peptide chain extension
• Intermediate for developing pharmaceutical peptides and custom library synthesis
• Research in biochemical assay development and structure–activity relationship studies

Safety & Handling

• Handling Precautions: Use appropriate PPE such as gloves, goggles, and lab coat. Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Storage Recommendations: Store tightly sealed at 2–8°C away from light and moisture for stability and integrity.
• Disposal: Dispose of waste in compliance with local, regional, and institutional safety guidelines.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Chemistry Expertise: Trusted source of high-purity protected amino acids and peptide intermediates, supporting global research and pharmaceutical innovation.
• Complete Documentation: Every batch supplied with COA, NMR, HPLC, and MS data for top-tier transparency and regulatory confidence.
• Flexible Supply & Custom Synthesis: Options for both research-scale and commercial production, with responsive expert support.
• Dedicated Technical Service: Guidance and assistance from inquiry through to application and troubleshooting for optimal research outcomes.

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Advance your peptide synthesis and biomedical research with SRIRAMCHEM’s premium Z-Trp-OMe. Contact us for latest pricing, sample availability, or project-specific synthesis solutions.