Z-Thr-OH

Z-Thr-OH (CAS No.: 19728-63-3, CAT No.: SRCZ-018) is a high-purity N-protected threonine derivative, commonly known as benzyloxycarbonylthreonine or Cbz-threonine. This compound incorporates the well-established benzyloxycarbonyl (Cbz or Z) protecting group on the amino terminus, facilitating selective protection during peptide synthesis to enable precise chain elongation and reduce side reactions.

Provided as a white to off-white crystalline powder with excellent purity (≥98%), Z-Thr-OH demonstrates strong chemical stability and is soluble in common organic solvents such as DMSO, DMF, and methanol. It has a molecular formula of C₁₂H₁₇NO₅ and a molecular weight of 247.27 g/mol, making it well-suited for solid-phase and solution-phase peptide synthesis in pharmaceutical research, biochemical studies, and medicinal chemistry applications.

Product Highlights

Technical Features & Benefits

• Classic Cbz (Benzyloxycarbonyl) Protection: Offers reliable protection of the amino group, enabling selective peptide bond formation and straightforward deprotection.
• High Purity & Consistency: Produced under stringent quality control to ensure batch-to-batch reproducibility and dependable synthesis outcomes.
• Excellent Solubility: Compatible with common peptide synthesis solvents such as DMSO and DMF, supporting diverse synthetic methodologies.
• Stable Crystalline Form: Facilitates easy handling, extended shelf life, and reliable storage stability.
• Versatile Intermediate: Ideal for use in peptide synthesis, medicinal chemistry research, and bioconjugation involving threonine residues.

Application Areas

• N-protected threonine for solid-phase and solution-phase peptide synthesis
• Intermediate in pharmaceutical and biochemical peptide research and development
• Precursor for peptidomimetic design and fragment-based drug discovery
• Building block for custom peptide libraries and medicinal chemistry projects

Safety & Handling

• Handling Precautions: Use personal protective equipment including gloves, goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact.
• Storage Recommendations: Store tightly sealed in a cool, dry, and dark place to maintain product integrity.
• Disposal: Dispose of waste according to local, regional, and institutional chemical safety regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Chemistry Expertise: Renowned supplier of high-purity N-protected amino acids and intermediates for research and pharmaceutical applications worldwide.
• Comprehensive Analytical Documentation: Full batch COA, NMR, HPLC, and MS data included to ensure regulatory compliance and quality transparency.
• Flexible Packaging & Custom Synthesis: Research-scale to bulk supply with technical support tailored to project requirements.
• Responsive Customer Service: Dedicated assistance for inquiries, ordering, and post-delivery technical support.

Request a Quote or Sample Today!

Enhance your peptide synthesis and medicinal chemistry research with SRIRAMCHEM’s premium Z-Thr-OH. Contact us for pricing, sample availability, or custom synthesis options tailored to your research needs.