Z-Ser-OH

Z-Ser-OH (CAS No.: 1145-80-8, CAT No.: SRCZ-024) is a high-purity N-protected serine derivative, commonly known as benzyloxycarbonylserine or Cbz-serine. This amino acid features the classic benzyloxycarbonyl (Cbz or Z) protecting group on the amino terminus, providing selective protection essential for peptide synthesis. Z-Ser-OH enables efficient chain elongation with minimal side reactions, making it a valuable building block in medicinal chemistry and peptide research.

Supplied as a white to off-white crystalline powder with excellent purity (≥98%), Z-Ser-OH exhibits high chemical stability and good solubility in polar organic solvents such as DMSO, DMF, and methanol. With a molecular formula of C₁₁H₁₃NO₅ and molecular weight of 239.22 g/mol, it is suitable for both solid-phase and solution-phase peptide synthesis, supporting research and pharmaceutical development workflows.

Product Highlights

Technical Features & Benefits

• Classic Cbz (Benzyloxycarbonyl) N-Protection: Ensures selective protection of the amino group, facilitating efficient peptide bond formation and clean deprotection.
• High Purity & Chemical Stability: Manufactured under strict quality control protocols assuring batch-to-batch consistency and performance.
• Good Solubility Profile: Compatible with major polar solvents used in peptide synthesis, enabling versatile workflow integration.
• Stable Crystalline Powder: Offers convenient handling, long shelf-life, and reliable storage under recommended conditions.
• Versatile Synthetic Intermediate: Suitable for peptide synthesis, medicinal chemistry, and biochemical research involving serine residues.

Application Areas

• N-protected serine for use in solid-phase and solution-phase peptide synthesis protocols
• Building block for pharmaceutical and biochemical peptide research and development
• Platform for peptidomimetic design, enzyme substrate synthesis, and bioconjugation strategies
• Fragment-based drug discovery and custom peptide library construction

Safety & Handling

• Handling Precautions: Use appropriate laboratory PPE including gloves, goggles, and lab coat. Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Storage Recommendations: Store in a tightly sealed container at 2–8°C, protected from moisture and light to maintain product quality.
• Disposal: Dispose of chemical waste in accordance with local, regional, and institutional regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Chemistry Expertise: Trusted global supplier of high-purity N-protected amino acids and intermediates with full analytical support.
• Complete Documentation: Each batch comes with COA, NMR, HPLC, and MS data ensuring quality assurance and compliance.
• Flexible Supply & Custom Synthesis: Options ranging from research-scale to bulk quantities with dedicated technical consultation.
• Responsive Customer Service: Professional assistance from inquiry through to delivery and post-sales support.

Request a Quote or Sample Today!

Enhance your peptide synthesis and medicinal chemistry projects with SRIRAMCHEM’s premium Z-Ser-OH. Contact us for pricing, sample availability, or customized synthesis solutions tailored to your research needs.