Z-Met-OH

Z-Met-OH (CAS No.: 1152-62-1, CAT No.: SRCZ-014) is a high-purity N-protected methionine derivative, commonly known as benzyloxycarbonylmethionine or Cbz-methionine. This compound features the classic benzyloxycarbonyl (Cbz or Z) protecting group on the amino terminus, providing selective protection essential for controlled peptide synthesis and enabling efficient chain elongation while reducing undesired side reactions.

Supplied as a white to off-white crystalline powder with excellent purity (≥98%), Z-Met-OH exhibits strong chemical stability and solubility in commonly used organic solvents such as DMSO, DMF, and methanol. With a molecular formula of C₁₃H₁₇NO₄S and a molecular weight of 263.34 g/mol, this compound is well-suited for both solid-phase and solution-phase peptide synthesis, supporting research, development, and pharmaceutical manufacturing applications.

Product Highlights

Technical Features & Benefits

• Classic Cbz (Benzyloxycarbonyl) Protection: Industry-standard for amino group protection, enabling selective peptide bond formation with controlled deprotection conditions.
• High Purity & Consistency: Manufactured under stringent quality controls ensuring reproducibility and high research reliability.
• Excellent Solubility Profile: Compatible with a wide range of organic solvents used in solid-phase and solution-phase peptide synthesis.
• Stable Crystalline Form: Ensures ease of handling, long shelf-life, and consistency in storage conditions.
• Versatile Building Block: Ideal for peptide synthesis, medicinal chemistry, and structural biology applications involving methionine residues.

Application Areas

• N-protected methionine for use in solid-phase and solution-phase peptide synthesis
• Intermediate in the development of synthetic peptides and peptide-based pharmaceuticals
• Platform for peptidomimetic design and biochemical research
• Fragment-based drug discovery and peptide therapeutic projects

Safety & Handling

• Handling Precautions: Use appropriate personal protective equipment, including gloves, goggles, and lab coat. Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Storage Recommendations: Store in a tightly closed container at 2–8°C, protected from light and moisture to maintain product integrity.
• Disposal: Dispose of chemical residues in accordance with local, regional, and institutional safety regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Science Expertise: Leading supplier of high-purity N-protected amino acids with detailed analytical support for pharmaceutical and research applications.
• Comprehensive Documentation: Each batch supplied with COA, NMR, HPLC, and MS data to ensure full quality and regulatory compliance.
• Flexible Supply & Custom Synthesis: Tailored options from research quantities to bulk production with technical consultation and support.
• Dedicated Customer Service: Expert guidance and responsive communication throughout procurement and project development.

Request a Quote or Sample Today!

Enhance your peptide synthesis and medicinal chemistry workflows with SRIRAMCHEM’s premium Z-Met-OH. Contact us for pricing, sample availability, or customized synthesis solutions to advance your research.