Z-Ile-OH

Z-Ile-OH (CAS No.: 3160-59-6, CAT No.: SRCZ-013) is a high-purity N-protected isoleucine derivative, also known as benzyloxycarbonylisoleucine or Cbz-isoleucine. This compound incorporates the classic benzyloxycarbonyl (Cbz or Z) protecting group on the amino terminus, providing selective protection essential for controlled peptide synthesis and enabling efficient chain elongation while minimizing side reactions.

Typically supplied as a white to off-white crystalline powder with excellent purity (≥98%), Z-Ile-OH demonstrates strong chemical stability and good solubility in organic solvents commonly used in peptide synthesis such as DMSO, DMF, and methanol. Its molecular formula is C₁₃H₂₁NO₄ with a molecular weight of 247.31 g/mol, making it suitable for both solid-phase and solution-phase peptide synthesis workflows across research, pharmaceutical, and biotechnological applications.

Product Highlights

Technical Features & Benefits

• Reliable Cbz (Benzyloxycarbonyl) N-Protection: Ensures selective amino group protection for clean peptide coupling and mild deprotection.
• High Purity and Batch Consistency: Manufactured under stringent quality controls for dependable and reproducible synthesis results.
• Good Solubility Profile: Compatible with most polar organic solvents used in manual and automated peptide synthesis workflows.
• Stable Crystalline Powder: Enables ease of handling, extended shelf-life, and consistency under standard storage conditions.
• Versatile Building Block: Suitable for medicinal chemistry, peptide synthesis, and biochemical applications involving isoleucine residues.

Application Areas

• N-protected isoleucine for use in solid-phase and solution-phase peptide synthesis
• Intermediate for peptide therapeutic development, medicinal chemistry, and bioconjugation
• Building block for peptidomimetic research and pharmaceutical synthesis
• Fragment-based drug design and peptide library construction

Safety & Handling

• Handling Precautions: Wear appropriate protective equipment including gloves, goggles, and lab coat. Avoid inhalation, ingestion, or contact with skin or eyes.
• Storage Recommendations: Store in a cool, dry, and dark place in tightly sealed containers to preserve product integrity.
• Disposal: Dispose of chemical waste in accordance with local, regional, and institutional regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Synthesis Specialists: Trusted provider of high-purity N-protected amino acids and intermediates with rigorous quality assurance.
• Comprehensive Analytical Documentation: Full COA, NMR, HPLC, and MS data accompanying every batch for reliable traceability.
• Flexible Supply & Customization: Options from research quantities to bulk production coupled with expert technical consultancy.
• Responsive Customer Support: Dedicated assistance from initial inquiry through to delivery and post-purchase application advice.

Request a Quote or Sample Today!

Advance your peptide synthesis projects and medicinal chemistry with SRIRAMCHEM’s premium Z-Ile-OH. Contact us for pricing, sample availability, or custom synthesis services tailored to your research needs.