Z-Gly-OH

Z-Gly-OH (CAS No.: 1138-80-3, CAT No.: SRCZ-001) is an essential N-protected glycine derivative, also known as benzyloxycarbonylglycine or Cbz-glycine, that is widely used as a building block in modern peptide synthesis and fragment-based drug design. With its classic Cbz (benzyloxycarbonyl, Z) protecting group, this compound offers a robust solution for controlled and selective synthesis of peptide chains, enabling research innovation in biochemistry, pharmaceuticals, and chemical biology.

Presented as a white to off-white crystalline powder, Z-Gly-OH demonstrates high purity (≥98%) and stability, ensuring consistent results even in complex synthetic workflows. Its molecular formula (C₁₀H₁₁NO₄), molecular weight (209.20 g/mol), and excellent solubility in common organic solvents such as DMSO, DMF, and methanol, make it an ideal choice for scale-up, analytical development, or automated peptide assembly.

Product Highlights

Technical Features & Benefits

• Czb-Protection: Well-established Z (Cbz/benzyloxycarbonyl) protecting group enables precise peptide coupling and clean deprotection, granting flexibility in synthetic strategies.
• High Purity & Consistency: Stringent quality control ensures reliability for solid-phase and solution-phase peptide synthesis.
• Excellent Solubility: Facilitates use in both automated and manual synthetic protocols across a range of solvent systems.
• Versatility: Serves as a starting material for peptidomimetic design, pharmaceutical intermediates, and fragment-based applications.
• Stable & Easy to Handle: Crystalline solid form offers safe storage, extended shelf-life, and reproducible handling in laboratory environments.

Application Areas

• N-protected glycine building block for peptide synthesis (SPPS and solution-phase)
• Intermediate in pharmaceutical ingredient development and custom peptide libraries
• Research on peptidomimetics, enzyme substrates, and bioconjugation approaches
• Fragment-based drug design and discovery of new therapeutic agents

Safety & Handling

• Handling Precautions: Use personal protective equipment (lab coat, gloves, goggles) and avoid inhaling dust or direct contact with skin and eyes.
• Storage Recommendations: Keep tightly closed in a cool, dry, and light-protected environment.
• Disposal: Dispose of in accordance with local and institutional chemical waste guidelines.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Chemistry Expertise: Supplying N-protected amino acids and advanced peptide intermediates for global R&D and industry leaders.
• Comprehensive Documentation: Full batch COA, NMR, HPLC, and MS spectral data provided for transparency and regulatory compliance.
• Flexible Supply & Custom Synthesis: Options for both research-scale and commercial production with technical support.
• Responsive Support: Guidance and order assistance from inquiry through to post-purchase application advice.

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Advance your peptide chemistry and research innovations with SRIRAMCHEM’s pure Z-Gly-OH. Contact us for pricing, samples, or project-customized synthesis solutions.