Z-Gly-OEt

Z-Gly-OEt (CAS No.: 1145-81-9, CAT No.: SRCZ-002) is a premium N-protected glycine ester recognized for its pivotal role in modern peptide synthesis and medicinal chemistry. Also known as ethyl N-[(benzyloxy)carbonyl]glycinate or Cbz-Glycine ethyl ester, this compound features a robust Cbz (benzyloxycarbonyl, Z) protecting group and an ethyl ester moiety, streamlining the assembly of peptide chains and enabling the creation of diverse peptide derivatives and related molecular scaffolds.

Typically supplied as a white or off-white crystalline powder with high purity (≥97%), Z-Gly-OEt combines chemical stability with excellent solubility in organic solvents such as DMSO, DMF, and ethanol. Its molecular formula is C₁₂H₁₅NO₄ with a molecular weight of 237.25 g/mol, making it suitable for reliable scale-up in automated synthesis, fragment-based design, and research-driven peptide development projects across pharmaceutical and biotechnological domains.

Product Highlights

Technical Features & Benefits

• Czb (Cbz/benzyloxycarbonyl) Protection: Delivers reliable amino protection for precise peptide assembly and selective deprotection in multi-step syntheses.
• Ethyl Ester Functionality: Streamlines peptide chain extension, ester hydrolysis, and fragment coupling for advanced synthetic protocols.
• Consistent Purity & Quality: Ensures dependable outcomes in both manual and automated synthesis platforms.
• Optimized Handling & Storage: Stable crystalline form guarantees ease of use, extended shelf-life, and excellent process reproducibility.
• Versatile Utility: Used as a starting material in peptide libraries, medicinal building blocks, and fragment-based drug design.

Application Areas

• N-protected glycine component for solid-phase and solution-phase peptide synthesis
• Peptidomimetic development and medicinal chemistry exploration
• Building block for pharmaceutical intermediates and custom research peptides
• Fragment-based drug discovery and screening workflows

Safety & Handling

• Handling Precautions: Wear protective gloves, goggles, and a lab coat. Avoid inhalation, ingestion, and skin or eye contact with powders or solutions.
• Storage Recommendations: Store tightly sealed in a cool, dry, and dark place, protected from moisture and oxidizing agents.
• Disposal: Dispose according to institutional, local, and national chemical safety regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Global Peptide Solutions: Expertise in N-protected amino acids and advanced synthesis intermediates for research, pharmaceutical, and biotech industries.
• Complete Analytical Documentation: Every batch supplied with COA, NMR, HPLC, and MS for full transparency and regulatory support.
• Flexible Packaging & Custom Orders: Research and bulk options available, including project-specific synthesis and consultation services.
• Responsive Technical Assistance: Customer support and guidance from inquiry through delivery and troubleshooting.

Request a Quote or Sample Today!

Drive success in your peptide synthesis and custom molecular design with SRIRAMCHEM’s high-quality Z-Gly-OEt. Reach out for pricing details, bulk samples, or tailored solutions for your next project.