Z-Gly-Gly-Phe-OH

Z-Gly-Gly-Phe-OH (CAT No.: SRCZ-010) is a specialized N-protected tripeptide acid widely used in peptide synthesis and biochemical research. This compound features the benzyloxycarbonyl (Cbz or Z) protecting group at the N-terminus combined with a free carboxylic acid at the C-terminus, making it an important intermediate for controlled and sequential peptide assembly as well as functional studies involving peptide bioactivity and structure-activity relationships.

Supplied as a high-purity white to off-white crystalline solid, Z-Gly-Gly-Phe-OH exhibits excellent solubility in common polar organic solvents such as DMSO, DMF, and methanol, and is compatible with both manual and automated peptide synthesis workflows. Its molecular composition supports versatile applications in drug discovery, enzymology, and peptide therapeutics research, providing a reliable building block for the creation of bioactive peptides and peptide-based molecules.

Product Highlights

Technical Features & Benefits

• Cbz N-Terminal Protection: Provides highly selective amino group protection essential for stepwise peptide synthesis and clean deprotection.
• Free Carboxyl Group: Enables versatile coupling strategies and further elongation or modification at C-terminus.
• High Purity & Stability: Maintains chemical integrity through stable storage conditions ensuring reliable synthetic results.
• Excellent Solubility: Compatible with major peptide synthesis solvents, facilitating ease of use in diverse synthetic routes.
• Versatile Peptide Building Block: Ideal for the synthesis of therapeutic peptides, peptidomimetics, and biochemical tool compounds.

Application Areas

• Use as an intermediate in solid-phase and solution-phase peptide synthesis
• Design and development of peptide therapeutics and biomolecular probes
• Medicinal chemistry projects focusing on enzyme inhibitors and receptor ligands
• Fragment-based drug discovery and peptide library construction

Safety & Handling

• Handling Precautions: Use appropriate laboratory protective equipment including gloves, goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact.
• Storage Recommendations: Store in tightly sealed containers at 2–8°C, protected from light and moisture to maintain product quality.
• Disposal: Dispose of chemical wastes as per local, regional, and institutional regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Chemistry Expertise: Leading supplier of N-protected peptides and intermediates for pharmaceutical research and development.
• Full Analytical Support: Comprehensive batch COA, NMR, HPLC, and MS documentation to ensure confidence in product quality.
• Flexible Supply & Customization: Options for research-scale to commercial production with tailored synthesis solutions available.
• Dedicated Customer Service: Responsive technical and order support throughout your project lifecycle.

Request a Quote or Sample Today!

Enhance your peptide synthesis and discovery projects with SRIRAMCHEM’s premium Z-Gly-Gly-Phe-OH. Contact us for pricing, sample availability, or custom synthesis services tailored to your needs.