Z-Gly-Gly-Phe-OCH₃

Z-Gly-Gly-Phe-OCH₃ (CAS No.: 13171-93-2, CAT No.: SRCZ-009) is a specialized N-protected tripeptide methyl ester used extensively in peptide synthesis and biochemical research. This compound, also recognized as benzyloxycarbonyl-glycylglycylphenylalanine methyl ester, features the classic Cbz (benzyloxycarbonyl, Z) protecting group on the N-terminus, combined with a methyl ester at the C-terminus, making it a key intermediate for controlled sequential peptide assembly and functional studies.

Offered as a white to off-white crystalline powder with a high purity level (≥98%), Z-Gly-Gly-Phe-OCH₃ shows excellent solubility in common polar organic solvents such as DMSO, DMF, and methanol. Its molecular formula is C₂₂H₂₆N₂O₅ with a molecular weight of 386.45 g/mol. The compound’s stability and reliable quality make it suitable for use in both research-scale peptide synthesis and structure-activity relationship studies.

Product Highlights

Technical Features & Benefits

• Cbz N-Terminal Protection: The benzyloxycarbonyl group ensures selective amino protection, facilitating clean, stepwise peptide chain assembly and mild deprotection conditions.
• Methyl Ester C-Terminal: Provides carboxyl protection ideal for controlled elongation and monitoring during peptide synthesis.
• High Purity and Reproducibility: Stringent quality control guarantees consistent batch-to-batch results essential for research and development.
• Excellent Solubility Profile: Compatible with organic solvents commonly used in automated and manual peptide synthesis methodologies.
• Versatile Peptide Intermediate: Enables synthesis of longer peptides, peptidomimetics, and biochemical probes.

Application Areas

• Solid-phase and solution-phase multistep peptide synthesis
• Building block for synthetic peptides, biomolecules, and drug discovery pipelines
• Research into peptide structure-activity relationships and enzymatic interactions
• Development of custom peptide libraries and biologically active sequences

Safety & Handling

• Handling Precautions: Use appropriate personal protection including gloves, goggles, and lab coat. Avoid ingestion, inhalation, and direct contact with skin or eyes.
• Storage Recommendations: Store in a cool, dry, and dark environment, tightly sealed to prevent moisture uptake.
• Disposal: Dispose of chemical waste in accordance with institutional, local, and regional regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Chemistry Expertise: Supplying high-purity protected peptides and amino acid derivatives for research, pharmaceutical, and industrial sectors.
• Strict Quality Assurance: Comprehensive analytical documentation including COA, NMR, HPLC, and MS provided with each batch.
• Flexible Supply and Custom Solutions: Production scalability and custom synthesis options tailored to project requirements.
• Dedicated Technical Support: Reliable customer service assisting throughout your procurement and application process.

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Accelerate your peptide synthesis and biochemical research with SRIRAMCHEM’s premium Z-Gly-Gly-Phe-OCH₃. Contact us for pricing, sample availability, or custom synthesis inquiries.