Z-Glu-OH

Z-Glu-OH (CAS No.: 1155-62-0, CAT No.: SRCZ-019) is a high-quality N-protected glutamic acid derivative widely used as an essential building block in peptide synthesis and medicinal chemistry. Also known as benzyloxycarbonylglutamic acid or Cbz-glutamic acid, this compound features the well-established benzyloxycarbonyl (Cbz or Z) protecting group on the amino terminus, enabling selective and efficient peptide bond formation while minimizing side reactions during multi-step syntheses.

Supplied as a white to off-white crystalline powder with excellent purity (≥98%), Z-Glu-OH shows strong chemical stability and good solubility in common organic solvents such as DMSO, DMF, and methanol. Its molecular formula is C₁₂H₁₃NO₆ and molecular weight is 283.24 g/mol. This compound is suitable for both solid-phase and solution-phase peptide synthesis, supporting pharmaceutical research, biochemical studies, and drug discovery efforts.

Product Highlights

Technical Features & Benefits

• Classic Cbz (Benzyloxycarbonyl) N-Protection: Enables selective amino protection for efficient and stepwise peptide synthesis with clean, mild deprotection procedures.
• High Purity & Consistency: Stringent quality control ensures reproducibility and dependable performance in synthetic workflows.
• Chemical Stability & Solubility: Well-suited for use in manual and automated peptide synthesis in solvents like DMSO and DMF.
• Stable Crystalline Powder: Facilitates easy handling, extended shelf life, and reliable storage under recommended conditions.
• Versatile Application: Suitable for peptide synthesis, medicinal chemistry research, drug discovery, and biochemical studies involving glutamic acid residues.

Application Areas

• N-protected glutamic acid for use in solid-phase and solution-phase peptide synthesis
• Intermediate in pharmaceutical peptide development and medicinal chemistry programs
• Building block for peptidomimetic design, enzyme substrate analogues, and fragment-based drug discovery
• Synthesis of custom peptide libraries and functional biochemical probes

Safety & Handling

• Handling Precautions: Use appropriate personal protective equipment such as gloves, goggles, and lab coat. Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Storage Recommendations: Keep the container tightly sealed in a cool, dry, and dark place to maintain product stability and quality.
• Disposal: Dispose of waste following local, regional, and institutional chemical safety regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Chemistry Expertise: Trusted supplier of high-purity N-protected amino acids and peptides supported with full analytical documentation for research and development.
• Comprehensive Quality Control: Batch COA, NMR, HPLC, and MS data supplied for regulatory compliance and quality assurance.
• Flexible Packaging & Custom Synthesis: Scalable options from research quantities to bulk production with expert technical support.
• Responsive Customer Service: Dedicated assistance from order placement through delivery and technical guidance.

Request a Quote or Sample Today!

Enhance your peptide synthesis and medicinal chemistry workflows with SRIRAMCHEM’s premium Z-Glu-OH. Contact us for pricing, sample availability, or custom synthesis solutions tailored to your research needs.