Z-Cys-OH

Z-Cys-OH (CAS No.: 53907-29-2, CAT No.: SRCZ-008) is a high-quality N-protected cysteine derivative, also known as benzyloxycarbonylcysteine or Cbz-cysteine, widely used as a key building block in peptide synthesis and pharmaceutical research. Featuring the classic Cbz (benzyloxycarbonyl, Z) protecting group on the amino function, this compound provides effective protection facilitating selective peptide bond formation and minimizing side reactions during multi-step synthesis sequences.

Presented as a white to off-white crystalline powder, Z-Cys-OH boasts excellent purity (≥98%) and chemical stability, making it highly suitable for both manual and automated peptide assembly techniques. Its molecular formula is C₁₂H₁₅NO₄S and its molecular weight is 241.32 g/mol. The compound shows good solubility in solvents commonly used in peptide chemistry such as DMSO, DMF, and methanol, while sparing water solubility ensures stability during storage and handling.

Product Highlights

Technical Features & Benefits

• Cbz (Benzyloxycarbonyl) Protection: Provides efficient N-terminal protection ensuring selective peptide bond formation and easy deprotection in complex synthetic sequences.
• High Purity and Quality: Strict manufacturing standards deliver consistent batch-to-batch performance for reproducible synthesis.
• Optimized Solubility: Compatible with common polar solvents used in automated and manual peptide synthesis protocols.
• Stable Crystalline Form: Ensures ease of handling, extended shelf-life, and reliable storage in typical laboratory conditions.
• Versatile Building Block: Widely used in peptide synthesis, pharmaceutical R&D, and bioconjugation applications involving cysteine residues.

Application Areas

• N-protected cysteine for solid-phase and solution-phase peptide synthesis
• Intermediate for peptide drug development, including disulfide bond formation
• Building block for bioconjugates, enzyme inhibitors, and customized peptide libraries
• Research in medicinal chemistry, proteomics, and biochemical assay design

Safety & Handling

• Handling Precautions: Use appropriate personal protective equipment including gloves, goggles, and lab coat. Avoid inhalation, ingestion, and contact with skin or eyes.
• Storage Recommendations: Store tightly closed in a cool, dry, and dark place to maintain product integrity.
• Disposal: Dispose according to local, regional, and institutional chemical safety regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Peptide Synthesis Expertise: Trusted supplier of high-purity N-protected amino acids and bespoke intermediates for pharmaceutical and biotechnological research.
• Comprehensive Quality Control: Full analytical documentation including COA, NMR, HPLC, and MS data provided with every batch.
• Flexible Supply and Custom Synthesis: From research quantities to bulk production with expert process support.
• Dedicated Customer Support: Responsive technical assistance and order management from inquiry to delivery.

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Support your peptide synthesis and medicinal chemistry programs with SRIRAMCHEM’s premium Z-Cys-OH. Contact us for pricing, sample availability, or tailored custom synthesis services.