Tropic acid

Essential precursor for anticholinergic drug synthesis with tropic acid (CAS No.: 529-64-6, CAT No.: SRCT-030). This ?-phenyl-?-hydroxypropionic acid serves as the critical acid component in atropine, scopolamine, and hyoscyamine manufacturing, enabling esterification with tropane alkaloids to produce muscarinic receptor antagonists for ophthalmology, gastroenterology, and anesthesiology.

With a molecular formula of C₉H₁₀O₃ and a molecular weight of 166.17 g/mol, DL-tropic acid appears as a white to off-white crystalline powder with a melting point of 116?118 ?C. Moderately soluble in water (20 g/L) and highly soluble in methanol, its chiral ?-center supports stereoselective synthesis of natural (-)-atropine via enzymatic resolution.

Product Highlights

Technical Features & Benefits

• • Atropine/Scopolamine Precursor: Direct esterification partner for tropane alkaloids producing clinically essential anticholinergics.

• • Chiral Synthesis Handle: Enzymatic resolution enables access to natural (-)-tropic acid for authentic alkaloid synthesis.

• • Crystalline Stability: Well-defined melting point (116?118?C) supports robust purification and GMP compliance.

• • Moderate Water Solubility: 20 g/L enables clean esterification in biphasic media with tropanol intermediates.

• • Process Proven: Documented in commercial atropine/scopolamine manufacturing with established analytical methods.

Application Areas

• • Synthesis of atropine sulfate for mydriasis, bradycardia reversal, and organophosphate poisoning.

• • Scopolamine hydrobromide production for motion sickness, preoperative sedation.

• • Hyoscyamine synthesis for irritable bowel syndrome and overactive bladder.

• • Chiral pool material for ?-aryl-?-hydroxy acid derivatives.

• • Analytical reference standard for tropane alkaloid quality control.

Safety & Handling

• • Eye/skin irritant; wear gloves, goggles, lab coat during handling.

• • Handle powders in well-ventilated area; avoid dust inhalation.

• • Store below 30?C in tightly closed containers; stable under ambient conditions.

• • Dispose of as chemical waste per pharmaceutical regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• • Proven expertise in tropane alkaloid intermediates and anticholinergic synthesis.

• • Custom chiral resolution and kilogram-scale tropic acid production.

• • Complete analytical package: COA, chiral HPLC, NMR, GC for pharmacopoeial compliance.

• Technical partnership for atropine/scopolamine process optimization and impurity control.

Request a Quote or Sample Today! Power your anticholinergic manufacturing with SRIRAMCHEM’s premium tropic acid. Contact the expert team for pricing, availability, or custom tropane intermediate requirements.

Contact us at research@sriramchem.com for pricing, sample availability, technical specifications, or custom synthesis inquiries.