(R)-(2,3-Dimethyl-3-((triethylsilyl)oxy)butyl)diphenylphosphine oxide

Enhance your advanced synthetic and pharmaceutical research with (R)-(2,3-Dimethyl-3-((triethylsilyl)oxy)butyl)diphenylphosphine oxide (CAS No.: 1227926-70-6, CAT No.: SRCD-004). This high-purity organophosphorus compound features a chiral diphenylphosphine oxide core functionalized with a 2,3-dimethyl-substituted butyl chain carrying a triethylsilyl ether protecting group. Its unique molecular architecture makes it valuable in stereoselective synthesis, ligand design, and as an intermediate in complex organophosphorus chemistry.

Possessing a diphenylphosphine oxide moiety, the compound exhibits Lewis base characteristics due to the phosphoryl (P=O) group, which is key in coordination chemistry and catalysis. The triethylsilyl (TES) group provides robust protection for the hydroxyl functionality, enhancing the compound’s stability and solubility in common organic solvents such as DCM, THF, and toluene, facilitating versatile synthetic applications.

Product Highlights

Technical Features & Benefits

• Chiral Phosphine Oxide Core: Enables stereoselective reactions and serves as a robust ligand or intermediate in asymmetric catalysis and organophosphorus chemistry.
• Triethylsilyl Ether Protection: Provides stability to the hydroxyl functionality and facilitates selective deprotection strategies in multi-step syntheses.
• High Chemical Purity: Stringently controlled production ensures consistent performance in complex synthetic routes.
• Good Solubility & Handling: Compatible with a wide range of organic solvents, enabling smooth process integration and ease of use.
• Versatile Application: Widely used in pharmaceutical intermediates, ligand development, and advanced organophosphorus synthetic methodologies.

Application Areas

• Asymmetric synthesis and chiral ligand design in organometallic catalysis.
• Pharmaceutical intermediate for the development of bioactive phosphorus-containing compounds.
• Advanced organic synthesis involving protected hydroxyl groups and stereocontrolled transformations.
• Research in stereoselective functionalization and catalytic reaction development.

Safety & Handling

• Precautions: Use appropriate personal protective equipment including gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact.
• Storage: Keep tightly sealed in a dry, cool, well-ventilated area, away from moisture and light.
• Disposal: Dispose of all chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Sophisticated facilities and skilled chemists ensure every batch meets stringent purity and stereochemical standards. Since 2013, SRIRAMCHEM supports innovative pharmaceutical and chemical research worldwide.
• Custom Synthesis: Tailored synthesis and scale-up options from milligram to multi-kilogram quantities, customized to your project needs with fast turnaround.
• Uncompromising Quality: Comprehensive analytical documentation including Certificate of Analysis (COA), NMR, HPLC, and MS data accompany each product for guaranteed identity and quality.
• Customer-Centric Support: Responsive technical and customer service teams collaborate closely to ensure your project success from inquiry to delivery.

Request a Quote or Sample Today!
Accelerate your chiral organophosphorus chemistry and pharmaceutical development with SRIRAMCHEM’s premium (R)-(2,3-Dimethyl-3-((triethylsilyl)oxy)butyl)diphenylphosphine oxide. Contact our expert team now for pricing, availability, or custom synthesis inquiries.