N-tert-butoxycarbonyl-O-tosyl-L-serine methyl ester

Streamline your peptide synthesis and organic chemistry research with N-tert-butoxycarbonyl-O-tosyl-L-serine methyl ester (CAS No.: 56926-94-4, CAT No.: SRCB-043), a high-purity, multifunctional, protected serine derivative. Equipped with an N-tert-butoxycarbonyl (Boc) group on the amino end and a tosyl group at the serine hydroxyl, this compound enables efficient, selective peptide coupling reactions and installation into sophisticated synthetic frameworks.

Its protected structure prevents undesired reactions at the amino and hydroxyl sites, making it a preferred intermediate for solid- and solution-phase peptide synthesis, natural product modification, and production of medicinally relevant molecules. With a molecular formula of C₁₆H₂₃NO₇S and molecular weight 373.42 g/mol, it typically appears as a white to off-white crystalline powder. This reagent achieves exceptional purity (≥95–98%), thermal stability, and solubility in commonly used organic solvents (e.g., DCM, DMF, acetonitrile).

Product Highlights

Technical Features & Benefits

• Protected Serine Ester: Boc and tosyl groups enable orthogonal deprotection and selective functionalization in peptide assembly.

• High-Purity, Reliable Performance: ≥95–98% purity ensures low byproducts and reproducibility in demanding synthetic protocols.

• Solid, Easily Handled Form: White crystalline powder for straightforward weighing and dissolution.

• Universal Solubility: Dissolves readily in standard organic solvents, making for flexible process development.

• Stable Under Recommended Storage: Maintains integrity at 2–8°C when protected from moisture and light.

Application Areas

• Solid- and solution-phase peptide synthesis as a protected serine reagent

• Intermediate for modified amino acid building blocks and side-chain elaboration

• Synthesis of complex natural products, peptidomimetics, and protease substrates

• Chemical biology, bioconjugation, and medicinal chemistry research

Safety & Handling

• Handling Precautions: Use gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and skin/eye contact.

• Storage Recommendations: Keep tightly closed in a cool (2–8°C), dry, well-ventilated area, away from acid/alkali and direct light.

• Disposal: Dispose of waste according to institutional or governmental hazardous waste protocols.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Advanced chemical processes, robust quality systems, and traceable documentation for every batch.
• Custom Synthesis: Flexible scales and modifications for R&D and bulk requirements, delivered with analytical support.
• Comprehensive Quality Control: COA, NMR, HPLC, and MS documentation supplied with each lot for confident use in regulated labs.
• Dedicated Support: Fast, knowledgeable response to all technical and logistical inquiries—partnering for your research success.

Request a Quote or Sample Today!
Accelerate your synthetic venture with SRIRAMCHEM’s high-purity N-tert-butoxycarbonyl-O-tosyl-L-serine methyl ester. Contact us for technical questions, pricing, or custom specifications tailored to your project.