H-Asn-OtBu·HCl

Enhance your peptide synthesis and medicinal chemistry workflows with H-Asn-OtBu·HCl (CAS No.: 63094-81-5, CAT No.: SRCA-020), a high-purity tert-butyl ester hydrochloride of L-asparagine. This protected amino acid derivative features a tert-butyl ester at the C-terminus and is supplied as its hydrochloride salt, making it ideal for selective peptide bond formation in both solid-phase and solution-phase syntheses. Its molecular formula is C₈H₁₇ClN₂O₃ and molecular weight is 224.69 g/mol.

H-Asn-OtBu·HCl is provided as a white to off-white crystalline powder and demonstrates excellent stability, high purity (≥98%), and robust solubility in polar organic solvents such as methanol, ethanol, and DMSO. This compound is widely used as a building block for peptide, peptidomimetic, and bioconjugate synthesis, supporting efficient, high-fidelity assembly of asparagine-containing sequences.

Product Highlights

Technical Features & Benefits

• Protected Amino Acid Derivative: Carbamide and tert-butyl ester groups enable selective peptide bond formation and orthogonal protection strategies.

• High Purity & Stability: Batch-to-batch reproducibility and stability under proper storage conditions for reliable synthesis protocols.

• Excellent Solubility: Dissolves readily in polar organic solvents, aiding in homogeneous peptide coupling and solution handling.

• Versatile Application: Suited for use as a building block in stepwise peptide synthesis and fragment couplings.

• Solid Form for Easy Handling: Crystalline powder allows for straightforward weighing, storage, and incorporation into synthetic workflows.

Application Areas

• Peptide synthesis (solid-phase and solution-phase) as a protected asparagine building block

• Development of bioactive peptide therapeutics and pharmaceutical intermediates

• Preparation of modified asparagine derivatives for structure–activity and functional studies

• Bioconjugation, labeling, and linker strategies in advanced biomolecular research

Safety & Handling

• Handling Precautions: Use appropriate protective equipment including gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact.

• Storage Recommendations: Store tightly closed under dry, cool, and light-protected conditions between 2–8°C.

• Disposal: Dispose of waste and residues following local, regional, and national environmental regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced production and quality control practices guarantee high purity and lot-to-lot reproducibility since 2013.
• Custom Synthesis: We offer tailored synthesis and custom supply from milligrams to multi-kilogram scale to support your research pipeline.
• Uncompromising Quality: Every batch is shipped with a full Certificate of Analysis (COA) and comprehensive analytical report.
• Customer-Centric Approach: Dedicated technical support and responsive services from inquiry to delivery for all your synthetic needs.

Request a Quote or Sample Today!
Accelerate your peptide synthesis and research with SRIRAMCHEM’s quality-assured H-Asn-OtBu·HCl. Contact our expert team for pricing, samples, or custom synthesis requests.