Myristic-gamma-picolinium chloride

Enhance your corticosteroid suspension formulations with Myristyl-?-picolinium chloride (CAS No.: 2748-88-1, CAT No.: SRCM-030). This C14 quaternary pyridinium surfactant serves as a key excipient in methylprednisolone acetate intra-articular suspensions, providing steric stabilization and controlled drug release for sustained anti-inflammatory action.

With a molecular formula of C₂₀H₃₆ClN and a molecular weight of 325.96 g/mol, it appears as an off-white to light brown solid. Slightly soluble in DMSO and methanol, its amphiphilic structure enables micelle formation and emulsion stabilization critical for long-acting injectable depot formulations.

Product Highlights

Technical Features & Benefits

• • Methylprednisolone Excipient: Essential surfactant component in Depo-Medrol? suspensions for intra-articular corticosteroid delivery.

• • C14 Amphiphilic Balance: Optimal hydrophilic-lipophilic balance (HLB) for micelle formation and steroid crystal stabilization.

• • Quaternary Ammonium Stability: Permanent positive charge ensures robust electrostatic stabilization in physiological conditions.

• • Pharmaceutical Grade Purity: ?97% purity suitable for injectable formulations and regulatory compliance.

• • Controlled Release Profile: Promotes sustained drug release kinetics critical for long-acting anti-inflammatory therapy.?

Application Areas

• • Excipient in methylprednisolone acetate depot suspensions for intra-articular injection.

• • Surfactant stabilizer for poorly water-soluble steroid microcrystals in sustained-release formulations.

• • Pharmaceutical intermediate for quaternary ammonium API synthesis.

• • Reference standard for excipient identity testing and formulation QC.

• • Research tool in micelle/drug delivery system development.

Safety & Handling

• • Toxic by ingestion; wear gloves, goggles, lab coat; avoid skin contact and inhalation.

• • Handle powders in fume hood; potential skin and respiratory irritant.

• • Store under inert atmosphere (N₂) at room temperature; hygroscopic material.

• • Dispose of as hazardous chemical waste per pharmaceutical regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• • Specialized expertise in pharmaceutical excipients, quaternary ammonium surfactants, and injectable formulation components.

• • Custom synthesis of C12-C18 picolinium homologues for tailored HLB requirements.

• • Comprehensive GMP analytical support: COA, NMR, HPLC, LC-MS for regulatory dossiers.
• Technical collaboration for depot formulation optimization and excipient qualification.

Request a Quote or Sample Today! Perfect your corticosteroid suspension formulations with SRIRAMCHEM’s premium Myristyl-?-picolinium chloride. Contact the expert team for pricing, availability, or custom surfactant development.