L-Phg-Otbu

Advance your peptide chemistry and chiral synthesis strategies with L-Phg-Otbu (CAS No.: 53934-78-4, CAT No.: SRCP-010). Also known as L-phenylglycine tert-butyl ester, this compound is a protected amino acid derivative featuring a tert-butyl ester group and the characteristic phenylglycine backbone. Its optically active (S)-configuration and robust ester protection make it a valuable building block for asymmetric synthesis, peptide assembly, and pharmaceutical research.

The molecular formula is C₁₂H₁₇NO₂ and the molecular weight is 207.27 g/mol. L-Phg-Otbu is typically supplied as a white to off-white crystalline powder with excellent solubility in organic solvents, such as dichloromethane, methanol, and ethyl acetate. The compound is highly stable under standard storage conditions, making it a convenient reagent for chemical and biochemical applications.

Product Highlights

Technical Features & Benefits

• Enantiopure Protected Amino Acid: Provides precise stereochemistry and effective carboxyl protection for peptide and small molecule synthesis.
• Stable tert-Butyl Ester Functionality: Enables compatibility with common deprotection strategies and multi-step reaction sequences.
• Chiral Auxiliary: Facilitates asymmetric catalysis and the synthesis of enantiomerically pure targets with high efficiency.
• Broad Applicability: Used in the synthesis of pharmaceuticals, peptide libraries, chiral drug intermediates, and bioconjugates.
• Analytical Documentation: Supplied with full COA, NMR, and HPLC analysis for assurance of quality and identity.

Application Areas

• Peptide synthesis and solid-phase peptide assembly
• Asymmetric synthesis and chiral catalysis
• Pharmaceutical research and active pharmaceutical ingredient (API) development
• Intermediate for agrochemicals and fine chemical production
• Structural and biochemical studies of enzyme mechanisms and protein interactions

Safety & Handling

• Wear appropriate PPE: gloves, lab coat, and goggles
• Avoid inhalation, ingestion, and contact with skin or eyes
• Store in a sealed container in a cool, well-ventilated area away from moisture and incompatible chemicals
• Dispose of waste in accordance with all applicable environmental regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Strict quality assurance and purity control since 2013
• Comprehensive batch-specific documentation and analytical support
• Custom synthesis and scalable production solutions
• Expert technical assistance and responsive customer service

Request a Quote or Sample Today!
Optimize your synthesis and research workflows with SRIRAMCHEM’s L-Phg-Otbu. Contact us now for pricing, samples, or custom synthesis inquiries.