K-Oxyma

Maximize efficiency and safety in peptide synthesis with K-Oxyma (CAS No.: 158014-03-0, CAT No.: SRCO-006). K-Oxyma, also known as Ethyl (hydroxyimino)cyanoacetate potassium salt or potassium salt of OxymaPure, is a cutting-edge coupling additive replacing hazardous reagents like HOBt or HOAt. Featuring improved thermal stability, non-explosive and non-allergenic properties, and enhanced suppression of epimerization and side reactions, K-Oxyma is ideal for demanding solid and solution phase peptide synthesis workflows.

The molecular formula is C₅H₅KN₂O₃ and the molecular weight is 180.20 g/mol. It commonly appears as a white to bright yellow crystalline or powdered solid, with a melting point range of 145–155°C. K-Oxyma possesses excellent solubility in common organic solvents, making it convenient for preparation of coupling mixtures in pharmaceutical, biotech, and materials science applications.

Product Highlights

Technical Features & Benefits

• Highly Efficient Coupling: Outperforms HOAt and rivals Oxyma Pure for peptide and amide bond formation, even on acid-labile resins.
• Non-Explosive and Safe: Offers superior safety compared to HOBt and HOAt, with non-allergenic and non-explosive characteristics.
• Thermal and Chemical Stability: Exhibits enhanced thermal resistance and a lower tendency for pressure release and decomposition.
• Epimerization Suppression: Minimizes racemization in peptide fragment condensation and carbodiimide-mediated couplings.
• Outstanding Purity: Supplied at ≥99% purity for reliable research and industrial applications.

Application Areas

• Solid-phase and solution-phase peptide synthesis
• Pharmaceutical development for safer API manufacturing
• Amide and ester formation in organic synthesis
• Bioconjugation and biotechnological applications
• Production of advanced polymers and materials
• Preparation of functional agrochemicals and specialty chemicals

Safety & Handling

• Wear suitable gloves, lab coat, and safety goggles when handling
• Avoid inhalation, ingestion, and skin or eye contact
• Use local exhaust and avoid generating dust
• Store in tightly closed containers, away from moisture and incompatible substances
• Dispose of waste according to local environmental regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Commitment to high purity, safety, and batch-to-batch reproducibility since 2013
• Comprehensive technical documentation, including COA and HPLC
• Custom synthesis and scalable production solutions
• Responsive customer support with expert guidance

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Achieve safer, more reliable peptide synthesis and organic transformations with SRIRAMCHEM’s products. Contact our team for pricing, samples, or custom synthesis requirements.