Isonipecotic acid

Advance your pharmaceutical synthesis and neuroscience research with Isonipecotic acid (CAS No.: 498-94-2, CAT No.: SRCI-006). Also known as 4-piperidinecarboxylic acid or hexahydroisonicotinic acid, this saturated heterocyclic compound features a piperidine ring with a carboxylic acid substituent at the 4-position.

Isonipecotic acid is a high-purity piperidine derivative valued as a GABA_A receptor partial agonist, making it a significant tool in neurological and receptor biology studies. As a pharmaceutical intermediate, it is actively used in synthesizing HDAC inhibitors, piperidine-based derivatives, and several CNS-active drug candidates. Its excellent solubility in water and stability under a wide range of conditions also support its role as a versatile building block in multi-step organic syntheses and medicinal chemistry.

Molecular formula: C₆H₁₁NO₂, Molecular weight: 129.16 g/mol. Supplied as a white to faint pink-beige crystalline powder, with a melting point above 300 °C (decomposition). Soluble in water, slightly soluble in alcohols, and stable at room temperature. Store in a cool, dry, dark place, protected from moisture and light. Purity ≥98%.

Product Highlights

Technical Features & Benefits

• Neurological Relevance: Partial agonist for GABA_A receptors—ideal for studies of inhibitory neurotransmission and CNS drug development.
• Versatile Intermediate: Used to produce HDAC inhibitors, piperidine-based drugs, and CNS-active compounds.
• High Purity: ≥98% purity for reproducible scientific and pharmaceutical applications.
• Stable Structure: Robust under standard laboratory conditions; shelf-stable in appropriate containers.
• Good Water Solubility: Supports use in diverse biological and synthetic chemistry workflows.

Application Areas

• Pharmaceutical intermediate for CNS and neurological therapeutics
• Research substrate for GABA_A receptor studies and inhibitory neurotransmission
• Intermediate in HDAC inhibitor and specialty piperidine compound synthesis
• Building block for heterocyclic and polymer chemistry

Safety & Handling

• Precautions: Warning—causes skin and serious eye irritation. May cause respiratory irritation. Use gloves, safety glasses, and lab coat. Avoid dust and vapors.
• Storage: Store tightly sealed, in a cool, dry, dark, and inert atmosphere, away from moisture and light.
• Disposal: Dispose of in accordance with local and national chemical safety regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Leading provider of high-purity heterocycles and intermediates since 2013.
• Custom Synthesis: Flexible quantities from research to industrial scale.
• Comprehensive Documentation: Supplied with COA and advanced analytical data for quality assurance.
• Responsive Customer Support: Fast, knowledgeable team supporting your R&D and production needs.

Request a Quote or Sample Today!
Power your synthetic and neurological research with SRIRAMCHEM’s quality-assured isonipecotic acid. Contact us for current pricing, shipment options, or custom supply requests.