Indole-3-carboxaldoxime

Advance your organic synthesis, medicinal chemistry, and analytical projects with Indole-3-carboxaldoxime (CAS No.: 2592-05-4, CAT No.: SRCI-012). Also known as indole-3-aldehyde oxime or 1H-indole-3-carboxaldehyde oxime, this compound features an indole core bearing an aldoxime functional group at the 3-position. The oxime moiety is formed via condensation of the corresponding aldehyde with hydroxylamine, conferring significant reactivity for ligand and heterocycle synthesis, as well as facilitating Schiff base and imine chemistry. Indole-3-carboxaldoxime is widely studied as an intermediate for biologically active indole derivatives, coordination complexes, and functional dyes. Due to the presence of both the indole and oxime motifs, it exhibits potential antimicrobial and anticancer bioactivities and is commonly used in fine chemical and pharmaceutical research.

Molecular formula: C₉H₈N₂O, Molecular weight: 160.17 g/mol. It appears as a red solid, melting point around 195 °C. It is soluble in acetone, dichloromethane, ethanol, ethyl acetate, and methanol. Purity is typically ≥98%. Store in a cool, dry, well-ventilated place, protected from light and moisture. Handle with care as it may cause skin, eye, and respiratory irritation; use appropriate personal protective equipment.

Product Highlights

Technical Features & Benefits

• Reactive Oxime Moiety: Enables ligand synthesis, Schiff base formation, and diverse heterocycle construction.
• Versatile Indole Scaffold: Ideal intermediate for bioactive indole derivatives in pharmaceuticals and fine chemicals.
• Physicochemical Stability: Red solid with high purity and a reliable melting point for synthetic reproducibility.
• Broad Solvent Compatibility: Dissolves in both polar protic and aprotic organic solvents for use in many reaction types.
• Potential Biological Activity: Used in antimicrobial and anticancer screening studies, supporting pharmaceutical innovation.

Application Areas

• Building block for complex indole derivatives, dyes, and ligands
• Intermediate for medicinal and agrochemical research
• Synthesis of Schiff bases, imines, and N-heterocycles
• Screening for biological activity (antimicrobial, anticancer)

Safety & Handling

• Precautions: Causes skin and eye irritation; may cause respiratory irritation. Avoid inhalation, ingestion, and contact with skin or eyes. Use gloves, goggles, and a lab coat; work in well-ventilated area.
• Storage: Store tightly sealed in a cool, dry, and dark place, protected from moisture.
• Disposal: Dispose in accordance with local, state, and national regulations for chemical waste.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Produced with tight quality controls and validated analytical methods for reliable results.
• Flexible Scale: Custom synthesis available from grams to multi-kilogram batches for R&D and commercial needs.
• Full Documentation: Every batch supplied with Certificate of Analysis (COA) and QC data.
• Supportive Service: Responsive technical and customer support at every stage of your project.

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