Indole-3-carboxaldehyde

Advance your pharmaceutical, biochemical, and materials research with Indole-3-carboxaldehyde (CAS No.: 487-89-8, CAT No.: SRCI-010). Also known as 1H-indole-3-carbaldehyde or 3-formylindole, this aromatic aldehyde features an indole ring substituted with an aldehyde functional group at the 3-position. It serves as an important building block in the synthesis of natural products, pharmaceuticals, and organic electronic materials. Indole-3-carboxaldehyde exhibits bioactivity as a plant metabolite and has demonstrated antifungal properties. It also acts as a receptor agonist at the aryl hydrocarbon receptor, modulating immune responses. This compound is widely used in the synthesis of heterocycles, Schiff bases, and various derivatives in medicinal chemistry and biochemical probe development.

Molecular formula: C₉H₇NO, Molecular weight: 145.16 g/mol. It appears as a white to yellow-orange crystalline powder with a melting point range of 193–200 °C. Slightly soluble in methanol and DMSO, insoluble in water. Sensitive to air and light; recommended storage is at room temperature in a cool, dark, and dry environment under inert gas. Purity is typically ≥98%.

Product Highlights

Technical Features & Benefits

• Aromatic Aldehyde Functionality: Enables Schiff base formation, reductive amination, and heterocyclic synthesis.
• Biologically Active Scaffold: Important intermediate in synthesizing bioactive natural products, pharmaceuticals, and agrochemicals.
• Physical Stability: Stable crystalline form facilitates handling and storage.
• Reactivity: Can be selectively functionalized at the aldehyde or indole moiety for diverse synthetic applications.
• High Purity: Ensures reliable results in medicinal chemistry and analytical studies.

Application Areas

• Synthesis of natural products and indole alkaloid derivatives
• Medicinal chemistry and drug discovery research
• Biochemical probe and sensor development
• Organic materials and dye synthesis

Safety & Handling

• Precautions: Wear appropriate PPE including gloves, goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact. Use in a well-ventilated area.
• Storage: Store in a sealed container, protected from light and moisture, preferably under inert atmosphere at room temperature or cooler.
• Disposal: Dispose of according to applicable local and national regulations for organic chemical wastes.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Consistent high-purity indole intermediates with stringent quality assurance.
• Custom Synthesis: Scalable production from lab research up to industrial quantities as required.
• Quality Control: Full analytical certification, including COA, NMR, and LC-MS, with each batch.
• Customer Support: Responsive scientific and technical team supporting your research and manufacturing goals.

Request a Quote or Sample Today!
Boost your synthetic capabilities with SRIRAMCHEM’s Indole-3-carboxaldehyde. Contact us for pricing, samples, or custom synthesis services.