Indole-3-carbinol

Advance your biomedical and nutraceutical research with Indole-3-carbinol (CAS No.: 700-06-1, CAT No.: SRCI-008). This compound, naturally found in cruciferous vegetables (such as broccoli, cabbage, and Brussels sprouts), is a prominent phytochemical and precursor to biologically active metabolites, including diindolylmethane (DIM). Indole-3-carbinol is primarily studied for its cellular antioxidant properties, role as a plant metabolite, and antineoplastic effects through modulation of estrogen metabolism and cell cycle regulation. It is frequently employed as a chemopreventive agent, in cancer research, and to elucidate mechanisms of hormone-dependent signal pathways.

Molecular formula: C₉H₉NO, Molecular weight: 147.18 g/mol. Supplied as an off-white to white crystalline powder. Melting point: 96–99 °C. Soluble in DMSO, ethanol, and methanol, but only slightly soluble in water (warm). Stable for extended periods under refrigeration (+4°C), protected from moisture and light. Minimum purity ≥96%.

Product Highlights

Technical Features & Benefits

• Antioxidant and Chemopreventive Agent: Modulates cell cycle, estrogen metabolism, and has demonstrated antineoplastic activity in research.
• Plant-Derived Metabolite: Occurs naturally in cruciferous vegetables and serves as a precursor to bioactive metabolites such as DIM (diindolylmethane).
• Biological Activity: Downregulates cell cycle-related proteins (CDK4, CDK6, cyclin D1, pRb) and interacts with hormone and signaling pathways.
• Useful in Nutraceutical Formulation: Incorporated in dietary supplements for health and preventive research.
• High Purity and Stability: For reproducible results and long shelf-life when properly stored.

Application Areas

• Cancer research and cell cycle studies
• Nutraceutical and dietary supplement development
• Plant metabolite and phytonutrient analysis
• Biochemical research on hormone regulation and receptor pathways

Safety & Handling

• Precautions: Use gloves, goggles, and protective clothing. Avoid inhalation, ingestion, and skin or eye contact. Work in a well-ventilated area.
• Storage: Keep tightly closed and protected from moisture and light, preferably at +4°C.
• Disposal: Dispose in accordance with local and national regulations on chemical waste.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Stringent quality standards and purity for research and commercial applications, since 2013.
• Flexible Supply: Research and production scale from grams to kilograms—custom solutions on demand.
• Full QA Documentation: Supplied with Certificate of Analysis (COA) and analytical data for each lot.
• Dedicated Support: Responsive and knowledgeable staff ready to help with technical and logistical needs.

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