H-Pro-Gly-Pro-OH

Advance your peptide and biomedical research with H-Pro-Gly-Pro-OH (CAS No.: 7561-51-5, CAT No.: SRCP-018). Also known as Pro-Gly-Pro (PGP), this tripeptide is derived from collagen degradation and is widely studied for its role as a neutrophil chemoattractant, biomarker for tissue remodeling, and signaling molecule in chronic inflammatory conditions. The presence of glycine flanked by proline residues confers conformational stability and distinct biological activity.

The molecular formula is C₁₂H₁₉N₃O₄ with a molecular weight of 269.30 g/mol. H-Pro-Gly-Pro-OH usually appears as a white to off-white crystalline powder and is highly soluble in water (up to 125 mg/mL at 20 °C with sonication). For best preservation of bioactivity, it is recommended to store this compound at -20 °C, protected from light and moisture.

Product Highlights

Technical Features & Benefits

• Biologically Active Tripeptide: Functions as a neutrophil chemoattractant implicated in tissue remodeling and inflammation.
• Stable Conformation: Glycine flanked by proline residues confer resistance to enzymatic degradation and maintain bioactivity.
• High Water Solubility: Facilitates dissolution for in vitro and in vivo biochemical assays.
• Research-Grade Purity: Supplied at ≥98% purity to ensure reproducible and robust experimental results.
• Supported by Literature: Validated in studies of immune regulation, tissue repair, and chronic inflammatory diseases.

Application Areas

• Research on neutrophil chemotaxis and immune response pathways
• Biomarker development for chronic obstructive pulmonary disease and tissue injury
• Peptide-based studies of extracellular matrix breakdown and remodeling
• Inflammatory disease models in vitro and in vivo
• Development and screening of inhibitors targeting peptide-mediated inflammatory pathways

Safety & Handling

• Wear appropriate PPE including gloves, lab coat, and eye protection
• Avoid inhalation, ingestion, and skin or eye contact
• Store in a sealed container at -20 °C, away from moisture and light
• Dispose of waste according to relevant regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Trusted provider of research peptides and high-grade chemical standards since 2013
• Complete batch-specific certificates including HPLC, NMR, and COA
• Custom synthesis and scalable production services
• Expert technical and customer support ensuring research success

Request a Quote or Sample Today!
Enhance your peptide-based research with SRIRAMCHEM’s premium H-Pro-Gly-Pro-OH. Contact us for pricing, samples, or custom synthesis support.