H-Lys-OMe·2HCl

Boost your peptide synthesis and bioconjugation research with H-Lys-OMe·2HCl (CAS No.: 26348-70-9, CAT No.: SRCL-006). Also known as L-lysine methyl ester dihydrochloride, this amino acid derivative contains both the carboxyl group protected as a methyl ester and the amino group protonated in the dihydrochloride salt form. It is a preferred reagent for solution-phase and solid-phase peptide synthesis (SPPS), introducing side-chain reactivity and enabling selective modifications of lysyl residues. The dual HCl stabilization enhances solubility, purity, and shelf-life while ensuring consistent handling in both research and production settings.

Molecular formula: C₇H₁₆N₂O₂·2HCl, Molecular weight: 233.14 g/mol. Appears as a white to almost white powder or crystal, melting point 197 °C, specific rotation +13° to +19° ([α]₂₀/D, c = 5, H₂O). It is highly soluble in water and hygroscopic; storage recommended at room temperature (<15°C optimal), in sealed packaging under inert gas.

Product Highlights

Technical Features & Benefits

• Methyl Ester Protection: Enables selective peptide elongation or derivatization at the carboxy-terminus.
• Dihydrochloride Salt Form: Enhances storage stability, handling, and aqueous solubility.
• High Reactivity & Stereochemistry: L-isomeric form for natural peptide sequences and pharmaceutical acceptability.
• Excellent Purity: Suitable for analytical, research, and cGMP applications.
• Versatile Peptide Synthon: Compatible with Fmoc, Boc, and other mainstream peptide synthesis protocols.

Application Areas

• Peptide and protein synthesis (SPPS, LPPS)
• Prodrug preparation and amino acid modification
• Research in proteomics, pharmaceuticals, and biochemistry
• Intermediate in specialty chemicals and API manufacture

Safety & Handling

• Precautions: Causes skin and eye irritation, may cause respiratory irritation. Avoid inhalation and direct contact; use PPE (gloves, goggles, coat).
• Storage: Store sealed, in a cool, dry, inert and dark place. Material is hygroscopic.
• Disposal: Dispose of according to local and national chemical regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• High Purity & Consistency: Manufactured to GMP-like standards with full QA documentation since 2013.
• Custom Order Quantities: Flexible supply from research scale to multi-kilo batches.
• Documentation: Delivered with a Certificate of Analysis (COA), purity, and technical data.
• Responsive Customer Support: Expert team ready to help with research and production needs.

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Drive your peptide research and manufacturing with SRIRAMCHEM’s H-Lys-OMe·2HCl. Contact us for pricing, samples, and technical consultations.