H-Leu-OMe.HCl

Advance your peptide synthesis and pharmaceutical research with H-Leu-OMe.HCl (CAS No.: 7517-19-3, CAT No.: SRCL-003). Also known as L-leucine methyl ester hydrochloride, this amino acid derivative features a protected carboxyl group (methyl ester) and a free amino group in the stable hydrochloride salt form. It is commonly used as a building block for solution-phase and solid-phase peptide synthesis, pharmaceutical intermediates, and biochemical modifications, owing to its high reactivity and well-defined stereochemistry. The compound is highly soluble in water, DMSO, and methanol, and offers excellent stability and handling due to the HCl salt form. High purity and batch consistency enable reproducible research and manufacturing outcomes.

Molecular formula: C₇H₁₅NO₂·HCl, Molecular weight: 181.66 g/mol. Appearance: white to almost white crystalline powder or crystals. Melting point: 150–153 °C (decomp.). Specific rotation: [α]₂₀/D +12° to +14° (c = 2% H₂O). Purity is ≥98%. The product is hygroscopic and should be stored under inert atmosphere at 2–8 °C, protected from moisture and light.

Product Highlights

Technical Features & Benefits

• Peptide Building Block: Ideal for solution-phase and solid-phase peptide synthesis requiring C-terminal methyl ester protection.
• Stable Hydrochloride Salt: Enhances compound stability and facilitates handling.
• Chiral Purity: L-form ensures optimal biological activity and compatibility.
• Reliable Performance: High batch consistency suitable for research and manufacturing scale-up.
• Broad Solubility: Soluble in both aqueous and organic solvents for flexible application.

Application Areas

• Peptide synthesis (SPPS/LPPS)
• Pharmaceutical intermediate and API building block
• Biochemical modification and derivatization
• Research and production in medicinal and analytical chemistry

Safety & Handling

• Precautions: Causes skin and eye irritation, may cause respiratory irritation. Use gloves, goggles, and lab coat. Avoid inhalation, ingestion, and contact with skin or eyes.
• Storage: Store sealed in a cool, dry, inert and dark environment (preferably 2–8 °C).
• Disposal: Dispose of in accordance with local/national regulations for organic chemicals and amino acid derivatives.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Consistent Quality: Manufactured under rigorous QC standards for research and industrial needs since 2013.
• Custom Synthesis: Provided in scalable quantities, individually packaged for research or bulk orders.
• Comprehensive Documentation: Full Certificate of Analysis (COA), NMR, and purity data with each batch.
• Expert Technical Support: Responsive scientific and logistical specialists to assist your project.

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Power your peptide and pharmaceutical synthesis with SRIRAMCHEM’s H-Leu-OMe.HCl. Contact us for real-time pricing, samples, or custom manufacturing.