H-Leu-AMC

Advance your enzymology and peptide research with H-Leu-AMC (CAS No.: 66447-31-2, CAT No.: SRCL-001). This fluorescently labeled dipeptide consists of L-leucine conjugated to 7-amino-4-methylcoumarin (AMC), a widely used fluorogenic reporter. The leucine residue provides specificity for protease and peptidase recognition, while the AMC moiety enables sensitive detection of enzymatic cleavage through fluorescence emission. H-Leu-AMC is used extensively in protease activity assays, kinetic studies, and high-throughput inhibitor screening. Its water solubility and stability make it suitable for in vitro and cell-based biochemical assays.

Molecular formula: C₁₆H₂₂N₂O₃, Molecular weight: approximately 282.36 g/mol. Supplied as a white to off-white fluorescent powder with ≥98% purity, ensuring reproducible and reliable experimental results.

Product Highlights

Technical Features & Benefits

• Fluorogenic Peptide Substrate: Enables sensitive and specific detection of leucine-preferring proteases.
• Stable and Pure: High purity guarantees reliable assay performance and reproducibility.
• Water Soluble: Suitable for aqueous and organic media in biochemical assays.
• Versatile Applications: Used in enzymatic activity screening, inhibitor analysis, and kinetic studies.
• Known Structure: Well-defined chemical with widely studied biochemical behavior.

Application Areas

• Protease and peptidase activity assays
• Enzyme kinetic studies
• High-throughput screening for inhibitor compounds
• Pharmaceutical and biochemical research

Safety & Handling

• Precautions: Use gloves, goggles, and lab coat. Avoid inhalation, ingestion, and contact with skin or eyes.
• Storage: Store sealed in a cool, dry, well-ventilated place away from light and moisture.
• Disposal: Dispose of in accordance with local and national regulations for chemical safety.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• High Purity Manufacturing: Produced under strict quality control for consistent batch purity and performance since 2013.
• Custom Synthesis: Scalable quality peptide substrates tailored to your research needs.
• Comprehensive Quality Documentation: Every batch includes Certificate of Analysis (COA) and advanced analytical data.
• Responsive Technical Support: Dedicated team ready to support your biochemical and pharmaceutical projects.

Request a Quote or Sample Today!
Elevate your enzymology studies with SRIRAMCHEM’s reliable H-Leu-AMC. Contact us for pricing, samples, or custom manufacturing inquiries.