H-Ile-OtBu.HCl

Expand your peptide synthesis toolbox with H-Ile-OtBu.HCl (CAS No.: 69320-89-4, CAT No.: SRCI-001). This derivative, L-isoleucine tert-butyl ester hydrochloride, features a fully protected isoleucine residue for efficient and selective peptide assembly. The tert-butyl ester protects the carboxyl group, allowing regioselective chain extension and cyclization during solid-phase or solution-phase peptide synthesis.

Hydrochloride salt form offers enhanced solubility and convenient handling. H-Ile-OtBu.HCl is compatible with Fmoc, Boc, and other standard protection strategies, exhibiting high purity, minimal racemization, and robust performance in automated or manual assemblies of peptides, peptidomimetics, and combinatorial libraries. Its properties make it ideal for preparing C-terminal tert-butyl protected peptide fragments and as a versatile building block in custom peptide workflows.

Molecular formula: C₁₀H₂₂ClNO₂, Molecular weight: 223.74 g/mol. White to off-white crystalline powder with ≥98% purity. Melting point: 160°C. Soluble in DMSO and other polar organic solvents; stable at room temperature when protected from moisture and stored in an inert atmosphere.

Product Highlights

Technical Features & Benefits

• Carboxyl-Protected Amino Acid: Prevents undesired side reactions, enabling precise peptide fragment assembly.
• Efficient Solubility and Handling: Hydrochloride salt enhances purification and application versatility.
• High Purity: Reliable results in solid-phase or solution-phase peptide synthesis.
• Broad Compatibility: Useful in Fmoc, Boc, and other standard protection strategies.
• Well-Defined Stereochemistry: Delivers reliable optical purity for demanding synthetic applications.

Application Areas

• Automated and manual solid-phase or solution-phase peptide synthesis
• Preparation of C-terminal tert-butyl protected peptide fragments
• Peptidomimetic and combinatorial library synthesis
• Pharmaceutical research and custom peptide production

Safety & Handling

• Precautions: Use proper PPE; avoid inhalation, ingestion, and skin or eye contact.
• Storage: Store tightly sealed at room temperature in an inert atmosphere, away from moisture and light.
• Disposal: Dispose of in accordance with local and national chemical regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: High-purity amino acid derivatives, rigorously analyzed and batch-consistent since 2013.
• Custom Synthesis: Production to your scale, from milligrams to multi-kilograms.
• Analytical Assurance: Full COA and advanced QC documentation (NMR, LC-MS, HPLC) provided.
• Responsive Support: Fast, helpful customer service at every step of your project.

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