H-Ile-OMe.HCl

Advance your peptide synthesis and biochemical research with H-Ile-OMe.HCl (CAS No.: 18598-74-8, CAT No.: SRCI-007). Also known as L-isoleucine methyl ester hydrochloride, this amino acid derivative features a methyl ester-protected carboxyl group and a free amino group, making it an essential building block for regioselective peptide synthesis and modification. The hydrochloride salt form enhances stability and solubility in polar solvents, optimizing reaction conditions in solution and solid-phase peptide synthesis. H-Ile-OMe.HCl is widely used in custom peptide synthesis, drug discovery, and protein engineering due to its high purity and well-defined stereochemistry, which match the natural L-configuration of isoleucine crucial for biological activity.

Molecular formula: C₇H₁₅NO₂·HCl, Molecular weight: 181.66 g/mol. It appears as a white to off-white crystalline powder with a melting point of 98-100°C and specific rotation [α]₂₀/D +27° (c = 2% in H2O). The compound is hygroscopic and soluble in methanol and DMSO, stable if stored under inert atmosphere at room temperature, preferably in a cool, dry place.

Product Highlights

Technical Features & Benefits

• High Purity Amino Acid Derivative: Suitable for sensitive peptide assembly and biological experiments.
• Stable Hydrochloride Salt: Enhances solubility and ease of handling in synthetic protocols.
• Well-defined Stereochemistry: Ensures accurate biological mimicry and peptide efficacy.
• Broad Compatibility: Supports Fmoc, Boc, and other common peptide synthesis strategies.
• Reliable Performance: Preferred building block in pharmaceutical research and custom peptide synthesis.

Application Areas

• Peptide synthesis and modification
• Pharmaceutical research and drug design
• Protein engineering and enzymatic studies
• Custom peptide and biologic manufacture

Safety & Handling

• Precautions: Wear gloves, goggles, and protective clothing. Avoid inhalation, ingestion, and contact with skin or eyes.
• Storage: Store in an inert atmosphere, protected from moisture and