H-His-Trp-OH

Power your peptide science and biochemical explorations with H-His-Trp-OH (CAS No.: 23403-90-9, CAT No.: SRCH-018). This dipeptide combines the properties of histidine and tryptophan, providing an aromatic-rich and functionally versatile structure used in peptide mapping, receptor-ligand research, bioactivity screening, and as a building block for peptide therapeutics. The imidazole side chain of histidine offers catalytic and metal-binding activity, while the indole moiety of tryptophan contributes to fluorescence, hydrophobic interactions, and protein structural motifs.

H-His-Trp-OH demonstrates good solubility in aqueous and polar solvents, giving it value for in vitro studies, biomolecular engineering, and enzyme-substrate research. Its stable peptide linkage and distinct physicochemical profile make it a choice reference standard and intermediate for advanced research and pharmaceutical development.Molecular formula: C₁₇H₁₉N₅O₃, Molecular weight: 341.36 g/mol. It typically appears as a white to off-white or pinkish powder with purity ≥98%, ensuring accuracy and repeatability in scientific experiments and synthesis workflows.

Product Highlights

Technical Features & Benefits

• Aromatic Dipeptide: Combines imidazole (histidine) and indole (tryptophan) for diverse biological activities and fluorescent properties.
• Catalytic & Binding Potential: Histidine’s side chain enables enzyme-like activity and metal coordination, supporting biocatalysis and analytical tagging.
• Spectral Application: Tryptophan’s indole group provides strong UV absorbance and intrinsic fluorescence for assay development.
• High Purity: Guarantees reproducibility in research and synthesis.
• Excellent Solubility: Compatible with water and organic solvents for flexible laboratory usage.

Application Areas

• Peptide synthesis and structure–activity relationship studies.
• Screening of dipeptides for antihypertensive or vasodilatory effects.
• Research on protein-ligand and protein–protein interactions.
• Fluorescence-based analytical and diagnostic applications.
• Pharmaceutical development of bioactive peptides and intermediates.

Safety & Handling

• Precautions: Use PPE including gloves, goggles, and lab coats. Avoid inhalation, ingestion, and skin or eye contact.
• Storage: Store sealed at 2–8°C in a cool, dry, well-ventilated location, away from light and moisture.
• Disposal: Dispose in accordance with local and national chemical waste guidelines.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Advanced equipment and expert chemists deliver high purity peptides, trusted since 2013 for biopharma R&D.
• Custom Synthesis: Milligram-to-multikilogram production, tailored for research or preclinical applications.
• Thorough Documentation: Full COA, NMR, LC-MS, and HPLC data with every batch for reliable research support.
• Dedicated Support: Fast, responsive, and collaborative service, from inquiry to delivery.

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