H-Glu(OMe)-OMe·HCl

Advance your peptide synthesis and medicinal chemistry research with H-Glu(OMe)-OMe·HCl (CAS No.: 23150-65-4, CAT No.: SRCG-003). This compound is the hydrochloride salt of glutamic acid dimethyl ester, featuring both the α- and γ-carboxyl groups protected as methyl esters and the free amino group stabilized as a hydrochloride salt. It serves as a valuable intermediate for peptide coupling, organic synthesis, and biochemical studies requiring protected glutamic acid derivatives.

With a molecular formula of C₇H₁₃NO₄·HCl and a molecular weight of approximately 195.64 g/mol, H-Glu(OMe)-OMe·HCl typically appears as a white to off-white crystalline solid. It is soluble in common organic solvents such as methanol, ethanol, and dichloromethane, facilitating diverse synthetic applications including solid-phase and solution-phase peptide synthesis.

Product Highlights

Technical Features & Benefits

• Hydrochloride Salt: Stabilizes the free amine group, enhancing shelf life and ease of handling.
• Dimethyl Ester Protection: Both carboxyl groups are methylated, providing protection during peptide synthesis and organic transformations.
• High Purity & Consistency: Manufactured under stringent quality control to ensure reproducible performance in synthetic workflows.
• Wide Solvent Compatibility: Excellent solubility in a variety of organic solvents enabling flexible synthetic applications.
• Versatile Intermediate: Useful in solid-phase and solution-phase peptide synthesis, chemical modifications, and biochemical research involving glutamic acid derivatives.

Application Areas

• Intermediate in solid-phase and solution-phase peptide synthesis (SPPS and LPPS) requiring protected glutamic acid residues.
• Synthesis of peptides, peptidomimetics, and related bioactive molecules.
• Utilized in medicinal chemistry and biochemical research involving ester-protected amino acids for improved process control.
• Building block for organic synthesis and structural analogues of glutamic acid.
• Applicable in enzyme substrate design and studies on peptide modifications.

Safety & Handling

• Wear appropriate personal protective equipment such as gloves, lab coat, and safety glasses.
• Avoid inhalation, ingestion, and contact with skin or eyes.
• Store sealed in a cool, dry, well-ventilated place, protected from moisture, heat, and light.
• Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing with rigorous quality control ensuring ≥98% purity and batch-to-batch consistency since 2013.
• Reliable supply supported by comprehensive analytical documentation, including Certificate of Analysis (COA), NMR, HPLC, and LC-MS for every batch.
• Custom synthesis and scale-up capabilities to meet research and industrial demands.
• Responsive technical support and dedicated customer service to assist with your project needs.

Request a Quote or Sample Today!
Enhance your peptide synthesis and medicinal chemistry projects with SRIRAMCHEM’s premium H-Glu(OMe)-OMe·HCl. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.