H-Cys(tBu)-OH·HCl

Advance your peptide synthesis and biochemical research with H-Cys(tBu)-OH·HCl (CAS No.: 2481-09-6, CAT No.: SRCC-012). This compound is S-tert-Butyl-L-cysteine hydrochloride, a protected form of the amino acid cysteine where the thiol group is shielded by a tert-butyl group to prevent unwanted side reactions during peptide assembly, improving synthesis selectivity and stability.

With the molecular formula C₇H₁₆ClNO₂S and a molecular weight of approximately 213.73 g/mol, it is supplied as a white to off-white crystalline powder. The hydrochloride salt form enhances solubility and stability, making it suitable for various organic solvents and aqueous media commonly used in solid-phase peptide synthesis (SPPS) and other biochemical applications.

Product Highlights

Technical Features & Benefits

• Thiolation Protection: The tert-butyl group protects the cysteine thiol, preventing oxidation and side reactions during peptide synthesis.
• Enhanced Stability: Hydrochloride salt form improves chemical stability and solubility in polar solvents.
• High Purity: Manufactured under strict quality control ensuring ≥98% purity suitable for sensitive synthetic applications.
• Versatile Solubility: Soluble in various organic solvents and aqueous media, facilitating diverse reaction conditions.
• Facilitates Peptide Synthesis: Ideal for solid-phase peptide synthesis (SPPS) allowing selective deprotection strategies.

Application Areas

• Use in solid-phase peptide synthesis as a cysteine thiol protecting group.
• Synthesis of peptides with controlled disulfide bond formation and folding.
• Biochemical studies involving cysteine-containing peptides and proteins.
• Organic synthesis requiring thiol-protected amino acid intermediates.

Safety & Handling

• Precautions: Use appropriate personal protective equipment such as gloves, safety glasses, and lab coat. Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Storage: Store tightly sealed in a cool, dry, and well-ventilated area away from light and moisture.
• Disposal: Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced facilities and experienced team ensure every batch is produced with extreme accuracy and high purity. As trusted industry leaders since 2013, we support pharmaceutical innovation, clinical research, and specialized testing globally.
• Custom Synthesis: We excel in custom synthesis, delivering tailored compounds from milligram to multi-kilogram scales with speed and precision.
• Uncompromising Quality: Each product is accompanied by full documentation including Certificate of Analysis (COA), NMR, LC-MS, and HPLC data to guarantee identity and purity.
• Customer-Centric Approach: Collaborative partnerships and responsive support prioritize your scientific goals from inquiry through delivery.

Request a Quote or Sample Today!
Accelerate your peptide synthesis and biochemical research with SRIRAMCHEM’s premium H-Cys(tBu)-OH·HCl. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.