H-Asp-OMe.HCl

Optimize your peptide synthesis and biochemical research with H-Asp-OMe.HCl (L-Aspartic acid dimethyl ester hydrochloride, CAS No.: 17812-32-7, CAT No.: SRCA-017), a high-purity amino acid derivative designed for efficient peptide coupling and advanced organic synthesis. This compound is characterized by its aspartic acid backbone with methyl ester protection at both carboxyl groups, presented as a stable hydrochloride salt. It has the molecular formula C₆H₁₁ClNO₄ and a molecular weight of 197.62 g/mol. The crystalline solid form exhibits excellent solubility in organic solvents such as methanol and DMSO, enabling seamless integration in solid-phase peptide synthesis (SPPS), Fmoc/tBu strategies, and custom peptide assembly workflows. With a purity of ≥98%, H-Asp-OMe.HCl is valued in pharmaceutical and biochemical R&D for its capacity to minimize side reactions and facilitate selective deprotection during multi-step syntheses.

Product Highlights

Technical Features & Benefits

• Protected Aspartic Acid Derivative: Contains methyl ester groups at both alpha- and beta-carboxyl positions, enabling selective deprotection and minimizing side reactions in peptide synthesis.

• High Purity & Stability: ≥98% purity ensures reproducible coupling efficiency and product consistency in solid-phase and solution-phase synthesis.

• Excellent Solubility: Readily soluble in common organic solvents like methanol and dimethyl sulfoxide (DMSO), facilitating convenient handling and incorporation into synthetic workflows.

• Versatile Application: Primarily used in Fmoc/tBu peptide synthesis and pharmaceutical intermediate production, suitable for both lab-scale and industrial peptide assembly.

• Stable Hydrochloride Salt: Improves storage stability, reducing degradation and extending shelf life under recommended conditions.

Application Areas

• Solid-phase peptide synthesis (SPPS) and custom peptide assembly

• Role as a protected building block in pharmaceutical and biochemical research

• Intermediate for synthesis of peptide-based drugs and enzyme substrates

• Custom synthesis requiring methyl ester protection for selective functional group manipulation

Safety & Handling

• Handling Precautions: Use appropriate PPE including gloves, lab coat, and safety goggles. Avoid inhalation, ingestion, and skin or eye contact.

• Storage Recommendations: Keep container tightly closed, stored in a cool, dry, ventilated area, protected from light and moisture.

• Disposal: Dispose of waste in accordance with local environmental regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced facilities and experienced team ensure that every batch of products are produced with extreme accuracy and high purity. As trusted industry leaders since 2013, our chemical solutions power pharmaceutical innovation, clinical research, and specialized testing worldwide.
• Custom Synthesis: Bring your vision to life! Our accomplished scientists are adept at custom synthesis—designing and producing unique compounds from milligrams to multi-kilogram lots, tailored to your specifications. Whether your needs are for a complex intermediate or novel building block, we deliver uncompromising results with speed and precision.
• Uncompromising Quality: SRIRAMCHEM’s products come with robust documentation, including a full Certificate of Analysis (COA) and advanced analytical data (NMR, LC-MS, HPLC), ensuring you receive molecules with verified identity and exceptional purity for every order.
• Customer-Centric Approach: We value collaborative partnerships. Our responsive support and custom solutions mean your scientific goals are always our top priority—from consultation to delivery and beyond.

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