H-Asn-OtBu.HCl

Enhance your peptide synthesis and biochemical research workflows with H-Asn-OtBu.HCl (L-Asparagine tert-butyl ester hydrochloride, CAS No.: 63094-81-5, CAT No.: SRCA-020), a high-purity protected amino acid derivative featuring tert-butyl ester protection on the side chain carboxamide of asparagine and presented as the stable hydrochloride salt. This compound has the molecular formula C₇H₁₄ClN₂O₃ and a molecular weight of 192.65 g/mol. It appears as a white to off-white crystalline powder having excellent chemical stability under recommended storage conditions. The tert-butyl (OtBu) protecting group safeguards the side-chain amide functionality, making H-Asn-OtBu.HCl particularly valuable for Fmoc/tBu solid-phase peptide synthesis (SPPS) and custom peptide assembly strategies. Soluble in common organic solvents such as methanol and dimethyl sulfoxide (DMSO), this reagent affords reliable coupling efficiency and minimal side reactions during peptide elongation. Guaranteed purity of ≥98% ensures consistent, reproducible results suitable for pharmaceutical research, biochemical studies, and synthetic organic chemistry applications.

Product Highlights

Technical Features & Benefits

• Protected Asparagine Derivative: Side-chain tert-butyl ester offers selective deprotection, minimizing side reactions and facilitating efficient peptide synthesis.

• High Purity & Stability: ≥98% purity ensures reproducible coupling and performance in both solid-phase and solution-phase peptide synthesis.

• Excellent Solvent Compatibility: Readily soluble in methanol, dimethyl sulfoxide (DMSO), and other polar organic solvents, enabling versatile synthetic applications.

• Stable Hydrochloride Salt: Enhances shelf-life and stability during storage, reducing degradation risks.

• Pharmaceutical & Biochemical Research Use: Widely used in peptide drug development, biochemical research, and custom synthesis of peptide building blocks.

Application Areas

• Solid-phase peptide synthesis (SPPS) incorporating protected asparagine residues

• Custom peptide assembly and pharmaceutical intermediate production

• Biochemical research involving modified amino acid derivatives

• Multi-step organic synthesis requiring selective tert-butyl protection

Safety & Handling

• Handling Precautions: Use appropriate PPE including gloves, lab coat, and eye protection. Avoid inhalation, ingestion, and skin or eye contact.

• Storage Recommendations: Keep container tightly closed; store in a cool, dry, well-ventilated place, protected from light and moisture.

• Disposal: Dispose of waste in compliance with local environmental regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced facilities and experienced team ensure that every batch of products are produced with extreme accuracy and high purity. As trusted industry leaders since 2013, our chemical solutions power pharmaceutical innovation, clinical research, and specialized testing worldwide.
• Custom Synthesis: Bring your vision to life! Our accomplished scientists are adept at custom synthesis—designing and producing unique compounds from milligrams to multi-kilogram lots, tailored to your specifications. Whether your needs are for a complex intermediate or novel building block, we deliver uncompromising results with speed and precision.
• Uncompromising Quality: SRIRAMCHEM’s products come with robust documentation, including a full Certificate of Analysis (COA) and advanced analytical data (NMR, LC-MS, HPLC), ensuring you receive molecules with verified identity and exceptional purity for every order.
• Customer-Centric Approach: We value collaborative partnerships. Our responsive support and custom solutions mean your scientific goals are always our top priority—from consultation to delivery and beyond.

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