Fmoc-Trp-OH

Advance your peptide synthesis, biochemical research, and medicinal chemistry with Fmoc-Trp-OH (CAS No.: 35737-15-6, CAT No.: SRCF-010). This high-purity amino acid reagent is N-α-Fmoc protected L-tryptophan, making it a fundamental building block for solid-phase peptide synthesis (SPPS), enzymatic studies, and the development of tryptophan-containing bioactive peptides and proteins.

The compound has a molecular formula of C₂₃H₂₀N₂O₄ and a molecular weight of approximately 388.42 g/mol. Fmoc-Trp-OH appears as a white to off-white crystalline powder with excellent solubility in polar aprotic solvents such as DMF, DMSO, and NMP, making it compatible with automated peptide synthesizers and manual protocols alike.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Provides stable, base-labile amine protection for efficient SPPS workflows and straightforward deprotection with piperidine.
• L-Tryptophan Residue: An essential aromatic amino acid for biological function, fluorescence studies, and structural analysis in peptides and proteins.
• High Purity: Research and pharmaceutical grade (≥98%) supports reproducible coupling and minimized side reactions.
• Excellent Solubility: Dissolves readily in common peptide synthesis solvents for robust incorporation into automated and manual synthesis.
• Versatile Intermediate: Critical for synthesizing tryptophan-containing peptides, analogues, and biomolecular probes.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS).
• Synthesis of tryptophan-rich peptides and therapeutic analogues.
• Development of peptide-based probes, bio-conjugates, and diagnostics.
• Fluorescence and structure-activity studies of proteins and enzymes.
• Protein engineering, enzymology, and pharmaceutical R&D.

Safety & Handling

• Use appropriate PPE: gloves, lab coat, safety goggles.
• Avoid inhalation, ingestion, and contact with skin or eyes.
• Store tightly sealed in a cool, dry, well-ventilated area, away from strong light and moisture.
• Dispose of waste in accordance with local and regional regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing and stringent quality control provide high-purity Fmoc-Trp-OH for research and production use.
• Custom synthesis and scale-up services for milligram to multi-kg quantities.
• Comprehensive product documentation: COA, NMR, HPLC, LC-MS available with each batch.
• Responsive customer support and technical consultation throughout your project lifecycle.

Request a Quote or Sample Today!
Accelerate your peptide and protein chemistry with SRIRAMCHEM’s premium Fmoc-Trp-OH. Contact our expert team for pricing, sample availability, or custom synthesis inquiries.