Fmoc-Phe-OH

Advance your peptide synthesis, medicinal chemistry, and bioactive molecule research with Fmoc-Phe-OH (CAS No.: 35661-40-6, CAT No.: SRCF-008). This high-purity amino acid derivative features L-phenylalanine protected at the N-terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it an essential building block for solid-phase peptide synthesis (SPPS), peptide modification, and structure-activity relationship studies.

The compound has a molecular formula of C₂₄H₂₁NO₄ and a molecular weight of approximately 387.43 g/mol. Fmoc-Phe-OH typically appears as a white to off-white crystalline powder and is easily soluble in standard peptide synthesis solvents such as DMF, DMSO, and NMP, facilitating efficient coupling and compatibility with automated and manual synthetic workflows.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Offers stable, base-labile protection of the amino group for stepwise SPPS and facile removal with piperidine.
• L-Phenylalanine Scaffold: Aromatic side chain supports π-stacking, hydrophobic interactions, and is a key contributor to peptide structure and function.
• High Purity & Batch Consistency: Quality controlled manufacturing ensures reliable, reproducible coupling and research-grade performance.
• Excellent Solubility: Dissolves easily in polar aprotic solvents used for peptide synthesis.
• Versatile Intermediate: Suitable for developing custom peptides, peptide-drug conjugates, and mimetics in research and pharmaceutical projects.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS)
• Preparation of custom peptide sequences and peptide-based therapeutics
• Medicinal chemistry research on phenylalanine-containing bioactive molecules
• Development of peptides for receptor targeting, enzyme inhibition, and diagnostics
• Structure-activity relationship (SAR) and protein engineering studies

Safety & Handling

• Use appropriate personal protective equipment including gloves, safety goggles, and lab coat
• Avoid inhalation, ingestion, and skin or eye contact
• Store tightly closed in a cool, dry, and well-ventilated area, away from moisture and strong light
• Dispose of chemical waste according to local, regional, and national regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing and stringent quality control for high-purity amino acid derivatives
• Custom synthesis and scale-up services from mg to multi-kg scale, tailored to your project needs
• Comprehensive product documentation including COA, NMR, HPLC, and LC-MS for each batch
• Rapid technical support and customer service for synthesis, ordering, and delivery queries

Request a Quote or Sample Today!
Accelerate your peptide synthesis and bioconjugation research with SRIRAMCHEM’s premium Fmoc-Phe-OH. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.