Fmoc-Met-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Met-OH (CAS No.: 71989-28-1, CAT No.: SRCF-031). This high-purity amino acid derivative features L-methionine protected at the N-terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it a crucial building block for solid-phase peptide synthesis (SPPS), methionine-containing peptide design, and protein engineering research.

The compound has a molecular formula of C₂₀H₂₁NO₄S and a molecular weight of approximately 371.45 g/mol. Fmoc-Met-OH typically appears as a white to off-white crystalline powder and demonstrates excellent solubility in standard peptide synthesis solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), ensuring compatibility with both manual and automated workflows.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Enables base-labile protection of the amino group for efficient SPPS through facile deprotection with piperidine.
• L-Methionine Residue: Features a thioether side chain important for protein function, oxidation studies, and bioactive peptide structure.
• High Purity & Batch Consistency: Produced under strict quality control, supporting reliable coupling and minimized side reactions.
• Excellent Solubility: Compatible with all standard peptide synthesis solvents; ideal for manual and automated processes.
• Versatile Application: Essential for the synthesis of methionine-containing peptides, enzymatic substrates, and protein engineering reagents.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS)
• Synthesis of peptides or proteins with N-terminal methionine
• Studies on methionine oxidation, redox biology, and protein modification
• Development of peptide-based probes, enzyme substrates, and therapeutics
• Research in proteomics, medicinal chemistry, and bioconjugation

Safety & Handling

• Use appropriate protective equipment: gloves, lab coat, and goggles
• Avoid inhalation, ingestion, or skin/eye contact
• Store tightly sealed, in a cool, dry, and well-ventilated place away from light and moisture
• Dispose of chemical waste according to relevant regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Specialized manufacturing and tight quality control for ≥98% purity and reproducibility since 2013
• Comprehensive analytical documentation including COA, NMR, HPLC, and LC-MS provided with every batch
• Reliable supply and custom synthesis from milligram to kilogram scale
• Experienced technical support and customer service throughout your research projects

Request a Quote or Sample Today!
Accelerate your peptide synthesis and protein research with SRIRAMCHEM’s premium Fmoc-Met-OH. Contact our expert team now for pricing, sample availability, or custom synthesis solutions.