Fmoc-Ile-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Ile-OH (CAS No.: 71989-23-6, CAT No.: SRCF-014). This high-purity amino acid derivative features isoleucine (Ile) protected at the amino terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it an essential building block for solid-phase peptide synthesis (SPPS), structural studies, and bioactive peptide development.

The compound has a molecular formula of C₂₁H₂₇NO₄ and a molecular weight of approximately 337.44 g/mol. Fmoc-Ile-OH is typically supplied as a white to off-white crystalline powder and dissolves readily in polar aprotic solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), facilitating efficient coupling in both automated and manual peptide synthesis workflows.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Provides stable and base-labile amino protection for efficient stepwise solid-phase peptide synthesis and easy deprotection with piperidine.
• Isoleucine Residue: A hydrophobic, branched-chain amino acid important in protein folding, interaction, and bioactivity.
• High Purity & Consistency: Manufactured with strict quality control ensuring reproducibility and reliable coupling efficiency.
• Excellent Solubility: Compatible with typical peptide synthesis solvents enabling smooth incorporation into automated and manual workflows.
• Versatile Intermediate: Widely used in peptide synthesis, medicinal chemistry, and structural biology applications.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS), including hydrophobic peptides
• Medicinal chemistry projects focusing on peptide-based drug development
• Research on peptide structure, folding, and interactions involving isoleucine residues
• Development of synthetic peptides, peptide conjugates, and bioactive molecules
• Studies of protein engineering, enzyme modulation, and bio-recognition mechanisms

Safety & Handling

• Use appropriate personal protective equipment including gloves, lab coat, and safety glasses
• Avoid inhalation, ingestion, and contact with skin or eyes
• Store sealed in a cool, dry, well-ventilated place protected from moisture, heat, and light
• Dispose of chemical waste in accordance with local, regional, and national regulations

Why Choose SRIRAM Laboratories Pvt. Ltd.?

• Expert manufacturing with rigorous quality control to ensure high purity and batch-to-batch consistency
• Custom synthesis capabilities, providing flexible scale-up from milligrams to kilograms to meet research needs
• Comprehensive batch documentation including Certificate of Analysis (COA), NMR, HPLC, and LC-MS
• Responsive technical support and customer service to assist throughout your project lifecycle

Request a Quote or Sample Today
Advance your peptide synthesis and medicinal chemistry research with SRIRAM’s premium Fmoc-Ile-OH. Contact our expert team now for pricing, availability, or custom synthesis inquiries.