Fmoc-Gly-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Gly-OH (CAS No.: 29022-11-5, CAT No.: SRCF-029). This high-purity amino acid derivative features glycine protected at the amino terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it an essential building block for solid-phase peptide synthesis (SPPS), peptide modification, and bioactive molecule design involving the simplest and most flexible amino acid residue.

The compound has a molecular formula of C₁₅H₁₁NO₄ and a molecular weight of approximately 285.25 g/mol. Fmoc-Gly-OH typically appears as a white to off-white crystalline powder and is soluble in common peptide synthesis solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), enabling efficient coupling and seamless incorporation into automated and manual peptide synthesis protocols.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Provides stable, base-labile protection of the amino group, ideal for stepwise SPPS with facile deprotection using piperidine.
• Glycine Residue: The simplest amino acid, offering conformational flexibility and minimal steric hindrance in peptide sequences.
• High Purity & Consistency: Manufactured under stringent quality control to ensure reproducibility and high coupling efficiency.
• Excellent Solvent Compatibility: Soluble in commonly used peptide synthesis solvents, enabling efficient automated and manual synthesis.
• Versatile Building Block: Widely used in peptide synthesis, medicinal chemistry, and structural biology research.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS), as a flexible amino acid building block
• Medicinal chemistry studies involving minimal side-chain interference
• Protein engineering and conformational studies requiring glycine incorporation
• Development of peptides, peptidomimetics, and bioactive molecules
• Research on peptide folding, dynamics, and secondary structure

Safety & Handling

• Use appropriate personal protective equipment including gloves, lab coat, and safety glasses.
• Avoid inhalation, ingestion, and contact with skin or eyes.
• Store tightly sealed in a cool, dry, well-ventilated area protected from moisture and light.
• Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert production with strict quality control to ensure high purity and batch-to-batch consistency.
• Reliable supply of research-grade Fmoc-Gly-OH with full analytical documentation (COA, NMR, HPLC, LC-MS).
• Custom synthesis and scalable production services from mg to multi-kg scale tailored to your project needs.
• Responsive technical support and customer service dedicated to your research success.

Request a Quote or Sample Today!
Advance your peptide synthesis and medicinal chemistry projects with SRIRAMCHEM’s premium Fmoc-Gly-OH. Contact our expert team for pricing, availability, or custom synthesis inquiries.