Fmoc-Gly-Gly-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Gly-Gly-OH (CAS No.: 35665-38-4, CAT No.: SRCF-038). This high-purity dipeptide consists of two glycine residues with an N-terminus protected by a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it an important building block for solid-phase peptide synthesis (SPPS), peptide modification, and bioactive molecule design involving flexible glycine-rich sequences.

The compound has a molecular formula of C₁₉H₁₆N₂O₅ and a molecular weight of approximately 344.33 g/mol. Typically supplied as a white to off-white crystalline powder, Fmoc-Gly-Gly-OH is soluble in common peptide synthesis solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), facilitating efficient coupling and incorporation into automated and manual peptide assembly workflows.

Product Highlights

Technical Features & Benefits

• Fmoc N-Terminus Protection: Provides stable, base-labile protection of the free amino group, suitable for stepwise solid-phase peptide synthesis and facile deprotection using piperidine.
• Dipeptide Structure: Consists of two glycine residues, offering minimal steric hindrance, conformational flexibility, and utility in peptide elongation strategies.
• High Purity & Batch Consistency: Manufactured under stringent quality control to ensure reproducibility and reliable coupling efficiency in peptide synthesis.
• Excellent Solubility: Soluble in polar aprotic peptide synthesis solvents facilitating efficient peptide assembly in both manual and automated workflows.
• Versatile Peptide Building Block: Useful in biochemical research, medicinal chemistry, and studies involving glycine-rich sequences or flexible spacers.

Application Areas

• Solid-phase peptide synthesis (SPPS) involving glycine dipeptide fragments.
• Peptide drug development and synthesis of flexible linker sequences.
• Construction of bioactive peptides, enzyme substrates, and protein analogues requiring glycine residues.
• Research in peptide folding, conformational flexibility, and structural biology.
• Use as an intermediate in the synthesis of glycine-containing peptides and peptidomimetics.

Safety & Handling

• Wear appropriate personal protective equipment including gloves, lab coat, and safety goggles.
• Avoid inhalation, ingestion, and skin or eye contact.
• Store tightly sealed in a cool, dry, well-ventilated area protected from moisture and light.
• Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing with stringent quality assurance ensuring ≥98% purity and reproducibility since 2013.
• Reliable supply of research-grade Fmoc-protected dipeptides with full analytical documentation including COA, NMR, HPLC, and LC-MS.
• Custom synthesis and scale-up services tailored to your peptide synthesis and pharmaceutical research needs.
• Responsive technical support and dedicated customer service throughout your research and development projects.

Request a Quote or Sample Today!
Advance your peptide synthesis and medicinal chemistry research with SRIRAMCHEM’s premium Fmoc-Gly-Gly-OH. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.