Fmoc-Glu-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Glu-OH (CAS No.: 121343-82-6, CAT No.: SRCF-019). This high-purity amino acid derivative features L-glutamic acid protected at the amino terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it an essential building block for solid-phase peptide synthesis (SPPS), peptide modification, and studies involving glutamic acid residues.

The compound has a molecular formula of C₁₅H₁₇NO₆ and a molecular weight of approximately 311.30 g/mol. Fmoc-Glu-OH typically appears as a white to off-white crystalline powder and is soluble in common peptide synthesis solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), facilitating efficient coupling and incorporation into automated and manual peptide synthesis protocols.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Provides a stable, base-labile protection of the amino group for efficient solid-phase peptide synthesis and straightforward deprotection using piperidine.
• L-Glutamic Acid Residue: Contains a free carboxyl side chain suitable for further functionalization, mimicking biological residues in peptides and proteins.
• High Purity & Consistency: Manufactured under stringent quality control to ensure reproducible coupling efficiency and reliable research outcomes.
• Excellent Solubility: Compatible with polar aprotic solvents commonly used in peptide synthesis for smooth incorporation into automated and manual protocols.
• Versatile Building Block: Widely used in peptide elongation, structural studies, and bioactive molecule development involving glutamic acid-containing sequences.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS) involving glutamic acid residues.
• Medicinal chemistry and drug discovery programs requiring glutamic acid-containing bioactive peptides.
• Preparation of peptide-based therapeutics, probes, and bioconjugates with carboxyl-functionalized side chains.
• Protein engineering and structural biology research focusing on acidic residue incorporation.
• Studies of peptide structure, binding interactions, and enzymatic activity involving glutamic acid.

Safety & Handling

• Use appropriate personal protective equipment including gloves, lab coat, and safety goggles.
• Avoid inhalation, ingestion, and contact with skin or eyes.
• Store tightly sealed in a cool, dry, and well-ventilated place, protected from moisture and direct light.
• Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing with stringent quality control ensures high purity and batch-to-batch consistency since 2013.
• Reliable supply and custom synthesis services tailored to specific peptide synthesis and pharmaceutical needs.
• Comprehensive documentation including Certificate of Analysis (COA), NMR, HPLC, and LC-MS documentation for each batch.
• Responsive technical support and dedicated customer service throughout your research projects.

Request a Quote or Sample Today!
Accelerate your peptide synthesis and medicinal chemistry research with SRIRAMCHEM’s premium Fmoc-Glu-OH. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.