Fmoc-Gln-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Gln-OH (CAS No.: 71989-20-3, CAT No.: SRCF-018). This high-purity amino acid derivative features L-glutamine protected at the amino terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it a vital building block for solid-phase peptide synthesis (SPPS), peptide modification, and bioactive molecule design involving glutamine residues.

The compound has a molecular formula of C₁₅H₁₈N₂O₅ and a molecular weight of approximately 286.31 g/mol. Fmoc-Gln-OH typically appears as a white to off-white crystalline powder, soluble in standard peptide synthesis solvents like dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), facilitating efficient coupling and incorporation into automated and manual peptide synthesis workflows.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Provides base-labile protection of the amino group, ideal for stepwise SPPS and facile deprotection with piperidine.
• Glutamine Residue: Contains a free side-chain amide suitable for peptide assembly and post-synthetic modifications.
• High Purity & Batch Consistency: Manufactured under strict quality controls ensuring reproducible coupling efficiency and product reliability.
• Solvent Compatibility: Soluble in common polar aprotic peptide synthesis solvents, enabling integration in automated and manual synthesis approaches.
• Versatile Intermediate: Widely used in biochemical, pharmacological, and structural studies involving glutamine-containing peptides.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS) involving glutamine residues.
• Medicinal chemistry and drug discovery programs requiring bioactive peptides.
• Development of peptide-based probes, therapeutics, and biomolecular conjugates.
• Protein engineering and structural biology research involving amide-containing side chains.
• Studies on peptide modification, binding interactions, and structure-activity relationships.

Safety & Handling

• Use appropriate personal protective equipment including gloves, lab coat, and safety goggles.
• Avoid inhalation, ingestion, and contact with skin or eyes.
• Store sealed in a cool, dry, and well-ventilated area away from moisture and direct light.
• Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing with stringent quality control since 2013, ensuring high purity and reproducibility.
• Reliable supply and custom synthesis services tailored to specific peptide synthesis needs.
• Comprehensive documentation including Certificate of Analysis (COA), NMR, HPLC, and LC-MS for every batch.
• Responsive technical support and dedicated customer service throughout your research lifecycle.

Request a Quote or Sample Today!
Accelerate your peptide synthesis and biochemical research with SRIRAMCHEM’s premium Fmoc-Gln-OH. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.