FMOC-Carbazate

Advance your peptide synthesis and organic chemistry research with FMOC-Carbazate (CAS No.: 35661-51-9, CAT No.: SRCF-005). This high-purity reagent features a carbazate (hydrazinecarboxylate) group protected by a 9-fluorenylmethyloxycarbonyl (FMOC) moiety, making it a specialized building block and coupling agent for the introduction of hydrazide or carbazate functionalities into peptides, proteins, and bio-conjugates.

FMOC-Carbazate is typically supplied as a white to off-white crystalline solid and displays excellent stability under standard laboratory conditions. The FMOC-protected hydrazine group is compatible with standard solid-phase peptide synthesis (SPPS) protocols, allowing selective deprotection and efficient conjugation to carboxylic acids, carbonyls, and activated esters.

Product Highlights

Technical Features & Benefits

• FMOC Protection: Provides base-labile protection for the hydrazine nitrogen, enabling clean removal with piperidine or similar bases during peptide synthesis.
• Carbazate Functionality: Useful for introducing hydrazide groups via standard peptide or small molecule coupling chemistry, facilitating the preparation of peptide hydrazides and subsequent modifications (e.g., ligation, cyclization, or bioconjugation).
• High Purity & Stability: Suited for sensitive synthetic applications, offering reliable performance and minimized side-product formation.
• Versatile Solubility: Compatible with common peptide synthesis solvents, simplifying process integration in both automated and manual workflows.
• Solid-Phase Peptide Synthesis (SPPS): Preferred in advanced peptide methodologies requiring a protected hydrazide or for linkage to solid supports.

Application Areas

• Preparation of C-terminal peptide hydrazides for chemical ligation or native chemical ligation.
• Installation of hydrazine groups in peptide, protein, or oligonucleotide synthesis.
• Development of bio-conjugates, linkers, and functionalized supports in chemical biology.
• Advanced medicinal chemistry and small molecule synthesis requiring protected hydrazide introduction.

Safety & Handling

• Use appropriate PPE: gloves, goggles, and lab coat.
• Avoid inhalation, ingestion, and contact with skin or eyes.
• Store tightly sealed, protected from light and moisture in a cool, dry place.
• Dispose of waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert synthesis and stringent quality controls for high-purity, research-grade FMOC-Carbazate.
• Comprehensive documentation: Certificate of Analysis (COA), NMR, HPLC, and LC-MS data accompany every batch.
• Custom synthesis scale-up and technical support to suit specialized project needs.
• Responsive service for consultation, technical inquiries, and delivery coordination.

Request a Quote or Sample Today!
Enhance your peptide, bioconjugation, and organic synthesis projects with SRIRAMCHEM’s premium FMOC-Carbazate. Contact our expert team now for pricing, sample availability, or custom synthesis support.