Fmoc-Asp-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Asp-OH (CAS No.: 119062-05-4, CAT No.: SRCF-036). This high-purity amino acid derivative features L-aspartic acid protected at the amino terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, making it an essential building block for solid-phase peptide synthesis (SPPS), peptide modification, and studies involving aspartic acid residues.

The compound has a molecular formula of C₁₅H₁₅NO₆ and a molecular weight of approximately 305.28 g/mol. Fmoc-Asp-OH typically appears as a white to off-white crystalline powder and is soluble in common peptide synthesis solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), facilitating efficient coupling and incorporation into automated and manual peptide synthesis workflows.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Provides stable, base-labile protection of the α-amino group, ideal for stepwise solid-phase peptide synthesis with facile deprotection by piperidine.
• Aspartic Acid Residue: Contains a β-carboxyl side chain offering opportunities for side-chain modifications and influencing peptide conformation and bioactivity.
• High Purity & Consistency: Manufactured under stringent quality control to ensure reproducible coupling efficiency and research reliability.
• Excellent Solvent Compatibility: Soluble in polar aprotic solvents commonly used in peptide synthesis, enabling efficient automated and manual protocols.
• Versatile Building Block: Widely used for peptide elongation, biochemical research, and pharmaceutical applications involving aspartic acid-containing peptides.

Application Areas

• Solid-phase and solution-phase peptide synthesis (SPPS) involving aspartic acid residues.
• Medicinal chemistry and drug discovery with focus on bioactive peptides containing Asp.
• Preparation of peptide therapeutics, enzyme substrates, and protein analogues featuring carboxyl functional groups.
• Protein engineering and structural biology studies related to acidic peptide sequences.
• Bioconjugation and peptide modification research involving side-chain functionalities of Asp.

Safety & Handling

• Use appropriate personal protective equipment such as gloves, lab coat, and safety glasses.
• Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Store tightly sealed in a cool, dry, well-ventilated area, protected from moisture and light.
• Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Experienced manufacturing ensuring consistent high purity and batch-to-batch quality since 2013.
• Reliable supply of research-grade Fmoc-Asp-OH with comprehensive analytical documentation (COA, NMR, HPLC, LC-MS).
• Custom synthesis and scale-up services tailored to your peptide synthesis and pharmaceutical development requirements.
• Responsive technical support and customer service to assist throughout your research lifecycle.

Request a Quote or Sample Today!
Enhance your peptide synthesis and medicinal chemistry research with SRIRAMCHEM’s premium Fmoc-Asp-OH. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.