Fmoc-Arg-OH

Advance your peptide synthesis and medicinal chemistry research with Fmoc-Arg-OH (CAS No.: 91000-69-0, CAT No.: SRCF-033). This high-purity amino acid derivative features L-arginine protected at the α-amino terminus with a 9-fluorenylmethoxycarbonyl (Fmoc) group, providing an essential building block for solid-phase peptide synthesis (SPPS), biochemical studies, and the preparation of arginine-containing bioactive peptides.

The compound has a molecular formula of C₂₂H₂₅N₇O₄ and a molecular weight of approximately 447.48 g/mol. Fmoc-Arg-OH typically appears as a white to off-white crystalline powder and is soluble in common polar aprotic peptide synthesis solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP), facilitating efficient coupling and compatibility with automated and manual peptide synthesis protocols.

Product Highlights

Technical Features & Benefits

• Fmoc Protection: Provides stable and base-labile protection of the α-amino group, allowing smooth stepwise solid-phase peptide synthesis with facile piperidine deprotection.
• Arginine Residue: Features a positively charged guanidine side chain critical for protein interaction, enzyme recognition, and bioactivity in peptides.
• High Purity & Consistency: Produced under rigorous quality control ensuring reproducible coupling efficiency and minimal side reactions.
• Excellent Solubility: Compatible with standard peptide synthesis solvents for automated and manual peptide assembly protocols.
• Versatile Intermediate: Widely used in the synthesis of arginine-containing peptides, peptide-drug conjugates, and biochemical probes.

Application Areas

• Solid-phase and solution-phase peptide synthesis involving arginine residues
• Preparations of bioactive peptides including cationic, cell-penetrating, and antimicrobial peptides
• Medicinal chemistry and pharmaceutical research for peptide-based therapeutics and enzyme substrates
• Development of peptide conjugates, protein engineering, and biochemical probes involving arginine
• Studies on peptide structure, function, and receptor binding involving basic amino acids

Safety & Handling

• Wear appropriate personal protective equipment including gloves, lab coat, and safety goggles
• Avoid inhalation, ingestion, and direct contact with skin or eyes
• Store sealed in a cool, dry, and well-ventilated area protected from moisture and light
• Dispose of chemical waste according to local, regional, and national regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing with stringent quality management ensuring ≥98% purity and batch-to-batch consistency
• Reliable supply of research-grade Fmoc-Arg-OH with full analytical documentation (COA, NMR, HPLC, LC-MS)
• Custom synthesis and scale-up services from milligram to multi-kilogram scale tailored to research and production needs
• Responsive technical and customer support assisting throughout the research and development process

Request a Quote or Sample Today!
Enhance your peptide synthesis and medicinal chemistry projects with SRIRAMCHEM’s premium Fmoc-Arg-OH. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.