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Research ChemicalsEthyl-2-ethoxy quinoline-1(2H)-carboxylate

SKU: SRCE-015

Name: Ethyl-2-ethoxy quinoline-1(2H)-carboxylate

Cat. NO.: SRCE-015

Cas. No.: 16357-59-8

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Description

Ethyl-2-ethoxy quinoline-1(2H)-carboxylate

Ethyl-2-ethoxy quinoline-1(2H)-carboxylate (CAS No.: 16357-59-8, CAT No.: SRCE-015) is a high-purity coupling reagent and intermediate, widely employed in peptide synthesis and advanced organic chemistry workflows. Also known as 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, EEDQ, or Ethyl 2-ethoxyquinoline-1(2H)-carboxylate, this compound offers exceptional efficiency in peptide bond formation with minimal racemization, making it a preferred choice in pharmaceutical research and development.

Supplied as a white to off-white crystalline powder with high purity (≥98%), it has a molecular formula of C14H17NO3 and a molecular weight of 247.29 g/mol. It demonstrates slight solubility in common organic solvents like chloroform, ethyl acetate, and methanol while being insoluble in water. Stored under inert atmosphere at 2–8°C, protected from light and moisture, it offers excellent stability for long-term use in both lab-scale and commercial synthesis.

Product Highlights

Attribute Details
Chemical Name Ethyl-2-ethoxy quinoline-1(2H)-carboxylate (EEDQ)
Synonyms 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline; EEDQ; Ethyl 2-ethoxyquinoline-1(2H)-carboxylate
Catalog Number SRCE-015
CAS Number 16357-59-8
Molecular Formula C14H17NO3
Molecular Weight 247.29 g/mol
Appearance White to off-white crystalline powder
Solubility Slightly soluble in chloroform, ethyl acetate, methanol; insoluble in water
Melting Point 62–67 °C
Boiling Point 125–128 °C at 0.1 mmHg
Storage Store under inert atmosphere at 2–8°C, protected from moisture and light
Purity ≥98%

Technical Features & Benefits

  • Highly Efficient Peptide Coupling: Facilitates rapid amide bond formation with minimal racemization.
  • Versatile Reagent: Suitable for amidation, esterification, and specialized organic transformations.
  • High Purity & Stability: Ensures reproducible performance for research and industrial synthesis.
  • Reliable Storage Life: Stable crystalline form under proper storage conditions for long-term usability.
  • Widely Trusted: Preferred choice in peptide and medicinal chemistry applications.

Application Areas

  • Peptide bond formation in solid-phase and solution-phase synthesis
  • Preparation of pharmaceutical intermediates and fine chemicals
  • Medicinal chemistry and structure–activity relationship (SAR) studies
  • Synthesis of specialty chemicals and sensor materials

Safety & Handling

  • Handling Precautions: Wear suitable protective clothing, gloves, and eye/face protection; avoid inhalation and contact with skin or eyes.
  • Storage Recommendations: Store under inert gas at 2–8°C, away from moisture and light.
  • Disposal: Dispose of contents/container according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

  • Synthesis Expertise: Reliable global supplier of high-quality peptide reagents and advanced research chemicals.
  • Comprehensive Documentation: Each batch provided with COA, NMR, HPLC, and MS data ensuring transparency and compliance.
  • Flexible Supply Options: Available from research to industrial scale with tailored technical support.
  • Customer-Centric Service: Prompt, professional assistance from inquiry to delivery.

Request a Quote or Sample Today!

Enhance your peptide synthesis workflows with SRIRAMCHEM’s premium-grade Ethyl-2-ethoxy quinoline-1(2H)-carboxylate (EEDQ). Contact us for competitive pricing, availability, or custom synthesis solutions tailored to your project requirements.

Additional information

Pack Size

1gm

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