Research ChemicalsEthyl-2-ethoxy quinoline-1(2H)-carboxylate
Name: Ethyl-2-ethoxy quinoline-1(2H)-carboxylate
Cat. NO.: SRCE-015
Cas. No.: 16357-59-8
- Description
- Datasheet
- Additional information
Description
Ethyl-2-ethoxy quinoline-1(2H)-carboxylate
Ethyl-2-ethoxy quinoline-1(2H)-carboxylate (CAS No.: 16357-59-8, CAT No.: SRCE-015) is a high-purity coupling reagent and intermediate, widely employed in peptide synthesis and advanced organic chemistry workflows. Also known as 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, EEDQ, or Ethyl 2-ethoxyquinoline-1(2H)-carboxylate, this compound offers exceptional efficiency in peptide bond formation with minimal racemization, making it a preferred choice in pharmaceutical research and development.
Supplied as a white to off-white crystalline powder with high purity (≥98%), it has a molecular formula of C14H17NO3 and a molecular weight of 247.29 g/mol. It demonstrates slight solubility in common organic solvents like chloroform, ethyl acetate, and methanol while being insoluble in water. Stored under inert atmosphere at 2–8°C, protected from light and moisture, it offers excellent stability for long-term use in both lab-scale and commercial synthesis.
Product Highlights
| Attribute | Details |
|---|---|
| Chemical Name | Ethyl-2-ethoxy quinoline-1(2H)-carboxylate (EEDQ) |
| Synonyms | 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline; EEDQ; Ethyl 2-ethoxyquinoline-1(2H)-carboxylate |
| Catalog Number | SRCE-015 |
| CAS Number | 16357-59-8 |
| Molecular Formula | C14H17NO3 |
| Molecular Weight | 247.29 g/mol |
| Appearance | White to off-white crystalline powder |
| Solubility | Slightly soluble in chloroform, ethyl acetate, methanol; insoluble in water |
| Melting Point | 62–67 °C |
| Boiling Point | 125–128 °C at 0.1 mmHg |
| Storage | Store under inert atmosphere at 2–8°C, protected from moisture and light |
| Purity | ≥98% |
Technical Features & Benefits
- Highly Efficient Peptide Coupling: Facilitates rapid amide bond formation with minimal racemization.
- Versatile Reagent: Suitable for amidation, esterification, and specialized organic transformations.
- High Purity & Stability: Ensures reproducible performance for research and industrial synthesis.
- Reliable Storage Life: Stable crystalline form under proper storage conditions for long-term usability.
- Widely Trusted: Preferred choice in peptide and medicinal chemistry applications.
Application Areas
- Peptide bond formation in solid-phase and solution-phase synthesis
- Preparation of pharmaceutical intermediates and fine chemicals
- Medicinal chemistry and structure–activity relationship (SAR) studies
- Synthesis of specialty chemicals and sensor materials
Safety & Handling
- Handling Precautions: Wear suitable protective clothing, gloves, and eye/face protection; avoid inhalation and contact with skin or eyes.
- Storage Recommendations: Store under inert gas at 2–8°C, away from moisture and light.
- Disposal: Dispose of contents/container according to local, regional, and national regulations.
Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?
- Synthesis Expertise: Reliable global supplier of high-quality peptide reagents and advanced research chemicals.
- Comprehensive Documentation: Each batch provided with COA, NMR, HPLC, and MS data ensuring transparency and compliance.
- Flexible Supply Options: Available from research to industrial scale with tailored technical support.
- Customer-Centric Service: Prompt, professional assistance from inquiry to delivery.
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Enhance your peptide synthesis workflows with SRIRAMCHEM’s premium-grade Ethyl-2-ethoxy quinoline-1(2H)-carboxylate (EEDQ). Contact us for competitive pricing, availability, or custom synthesis solutions tailored to your project requirements.
Additional information
| Pack Size | 1gm |
|---|






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