Dibromobimane

Enhance your biochemical analysis and advanced synthetic research with Dibromobimane (CAS No.: 68654-25-1, CAT No.: SRCD-024). Also known as bimane, dibromo- or 1,2-dibromoethane-1,2-diylbis(2,1-benzoxazole), this high-purity heterocyclic reagent is renowned for its utility as a fluorogenic derivatization agent and thiol-specific labeling reagent in protein and peptide chemistry, cell biology, and analytical applications.

With a molecular formula of C₈H₆Br₂N₂O₂ and a molecular weight of 341.96 g/mol, Dibromobimane typically appears as a pale yellow or off-white solid. Its bimane core, functionalized with two bromine atoms, enables rapid and highly specific reaction with thiol groups, leading to stable and fluorescent bimane adducts. It is soluble in DMSO, DMF, and other organic solvents, facilitating integration into biological, environmental, and analytical workflows.

Product Highlights

Technical Features & Benefits

• Thiophilic Reagent: Highly selective for sulfhydryl (–SH) groups in biological and synthetic samples, allowing for site-specific tagging and crosslinking.
• Fluorescent Derivatization: Enables sensitive detection and quantification of thiols by forming intensely blue-fluorescent bimane adducts for HPLC, fluorescence microscopy, and flow cytometry.
• High Purity & Stability: Guarantees reproducibility and low background in sensitive analytical applications.
• Good Organic Solvent Compatibility: Facilitates integration with a wide range of biological and chemical systems.
• Broad Utility: Widely used in redox biology, diagnostics, proteomics, and environmental monitoring of thiol-containing compounds.

Application Areas

• Protein and peptide labeling/derivatization for structural and functional analysis
• Quantitative thiol analysis in biochemical and environmental samples
• Fluorescence-based detection of reduced and oxidized species in cell biology
• Site-specific cross-linking and mapping of disulfide bonds
• Reagent in redox state studies and protein folding research

Safety & Handling

• Precautions: Wear appropriate PPE (gloves, lab coat, safety glasses). Avoid inhalation, ingestion, and skin/eye contact. Reacts with thiols; use in a well-ventilated area.
• Storage: Store tightly sealed at −20°C, protected from moisture and light to prevent decomposition.
• Disposal: Dispose of waste in accordance with local, regional, and national regulations for hazardous chemical reagents.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our state-of-the-art facilities and team of specialists ensure stringent quality control, guaranteeing high-purity dibromobimane for research applications worldwide.
• Custom Synthesis: We offer rapid, tailored synthesis and scale-up from milligram to kilogram quantities to meet your precise specification needs.
• Full Analytical Documentation: Each batch is delivered with detailed Certificate of Analysis (COA), NMR, LC-MS, and HPLC data for identity and purity confirmation.
• Responsive Support: Dedicated customer service and technical consultation are available from inquiry through delivery and beyond.

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Advance your biochemical and analytical research with SRIRAMCHEM’s premium Dibromobimane. Contact our expert team now for pricing, sample availability, or custom synthesis support.